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ChemicalBook >> CAS DataBase List >>1-(4-BOC-piperidyl)-4-iodopyrazole

1-(4-BOC-piperidyl)-4-iodopyrazole

1-(4-BOC-piperidyl)-4-iodopyrazole Structure
1-(4-BOC-piperidyl)-4-iodopyrazole structure
CAS No.
877399-73-0
Chemical Name:
1-(4-BOC-piperidyl)-4-iodopyrazole
Synonyms
tert-butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate;Crizotinib Impurity 16;CrizotinibIntermediate1;1-(4-BOC-piperidyl)-4-iodopyrazole;1-(4-BOC-piperazino)-4-iodopyrazole;1-(1-Boc-4-piperidinyl)-4-iodopyrazole;1-Boc-4-(4-iodo-1H-pyrazol-1-yl)piperidine;1-(1-Boc-4-piperidinyl)-4-iodopyrazole, 98%;4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate;tert-Butyl 4-(4-iodopyrazolyl)piperidinecarboxylate
CBNumber:
CB32473791
Molecular Formula:
C13H20IN3O2
Molecular Weight:
377.22
MDL Number:
MFCD12913927
MOL File:
877399-73-0.mol
MSDS File:
SDS
Last updated:2024-06-27 15:15:15
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1-(4-BOC-piperidyl)-4-iodopyrazole Properties

Melting point 97 °C
Boiling point 430.6±35.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
form Solid
pka 1.08±0.19(Predicted)
Sensitive Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a

1-(4-BOC-piperidyl)-4-iodopyrazole price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H65918 1-(1-Boc-4-piperidinyl)-4-iodopyrazole, tech. 90% 877399-73-0 1g $159 2021-12-16 Buy
Alfa Aesar H65918 1-(1-Boc-4-piperidinyl)-4-iodopyrazole, tech. 90% 877399-73-0 5g $631 2021-12-16 Buy
Alfa Aesar H65918 1-(1-Boc-4-piperidinyl)-4-iodopyrazole, tech. 90% 877399-73-0 250mg $53 2021-12-16 Buy
TRC B809635 tert-Butyl4-(4-Iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate 877399-73-0 25g $130 2021-12-16 Buy
American Custom Chemicals Corporation HCH0037519 1-(4-BOC-PIPERAZINO)-4-IODOPYRAZOLE 95.00% 877399-73-0 1G $848.93 2021-12-16 Buy
Product number Packaging Price Buy
H65918 1g $159 Buy
H65918 5g $631 Buy
H65918 250mg $53 Buy
B809635 25g $130 Buy
HCH0037519 1G $848.93 Buy

1-(4-BOC-piperidyl)-4-iodopyrazole Chemical Properties,Uses,Production

Synthesis

1-(4-BOC-piperidyl)-4-iodopyrazole is prepared by the reaction of 4-Iodopyrazole and 1-Boc-4-methanesulfonyloxypiperidine. The specific synthesis steps are as follows:
To a stirred solution of 4-iodo-lH-pyrazole (8.98 g, 46.28 mmol) in DCM (160 mL) was added NaH (1.67 g, 55.53 mmol, 80percent NaH/mineral oil) portion-wise at 0 °C. The mixture was stirred at 0 °C for 1 hour, then tert-butyl 4-((methylsulfonyl)oxy)piperidine-l- carboxylate (14.22 g, 50.90 mmol) was added. The resulted mixture was stirred at 100 °C for 15 hours, then cooled to rt, quenched with H20 (30 mL) and concentrated in vacuo. The residue was diluted with H20 (150 mL), and the mixture was extracted with EtOAc (100 mL x 5). The combined organic layers were dried over anhydrous Na2S04 and concentrated in vacuo. The residue was purified by a silica gel column chromatography (PE/EtOAc (v/v) = 5/1) to give 1-(4-BOC-piperidyl)-4-iodopyrazole as a white solid (12.25 g, 70.2percent>). MS (ESI, pos. ion) m/z: 322.0 (M-56+1).
-(4-BOC-piperidyl)-4-iodopyrazole synthesis

1-(4-BOC-piperidyl)-4-iodopyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-BOC-piperidyl)-4-iodopyrazole Suppliers

Global( 173)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20285 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
HaBo Hong Kong Co., Limited. 		+86-25-18512596065 info@habotech.com CHINA 933 58
Shanghai Worldyang Chemical Co.,Ltd. 		+86-021-56795779 +8613651600618 sales@worldyachem.com China 1243 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
HaBo Hong Kong Co., Limited. 		58
Shanghai Worldyang Chemical Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58

View Lastest Price from 1-(4-BOC-piperidyl)-4-iodopyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-PIPERIDINECARBOXYLIC ACID 4-(4-IODO-1H-PYRAZOL-1YL)-,1-1-DIMETHYLETHYLESTER pictures 2024-01-02 1-PIPERIDINECARBOXYLIC ACID 4-(4-IODO-1H-PYRAZOL-1YL)-,1-1-DIMETHYLETHYLESTER
877399-73-0
 US $200.00-1.00 / KG 1KG 99%, 99.5% Sublimated g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester pictures 2022-10-09 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester
877399-73-0
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester pictures 2021-07-13 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester
877399-73-0
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

877399-73-0(1-(4-BOC-piperidyl)-4-iodopyrazole)Related Search:

Pyrazole Piperidinylpiperidine
1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester 1-(4-BOC-piperazino)-4-iodopyrazole 1-(4-BOC-piperidyl)-4-iodopyrazole 1-Boc-4-(4-iodo-1H-pyrazol-1-yl)piperidine 4-(4-Iodo-pyrazol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester tert-Butyl 4-(4-iodopyrazolyl)piperidinecarboxylate 1-Piperidinecarboxylic acid, 4-(4-iodo-1H-pyrazol-1-yl)- 1-(1-Boc-4-piperidinyl)-4-iodopyrazole tert-butyl 4-(4-iodopyrazol-1-yl)piperidine-1-carboxylate Crizotinib Impurity 16 tert-butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate 1-(1-Boc-4-piperidinyl)-4-iodopyrazole, 98% CrizotinibIntermediate1 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate 877399-73-0 877399-70-3