ChemicalBook >> CAS DataBase List >>4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride
- CAS No.
- 1185136-22-4
- Chemical Name:
- 4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride
- Synonyms
- LP 12 hydrochloride;LP 12 hydrochloride hydrate;LP-12 hydrochloride, 5-HT7 agonist;4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride;6-(4-([1,1'-Biphenyl]-2-yl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
- CBNumber:
- CB32518702
- Molecular Formula:
- C32H40ClN3O
- Molecular Weight:
- 518.1325
- MDL Number:
- MFCD11114387
- MOL File:
- 1185136-22-4.mol
Last updated:2025-01-27 09:38:02
| storage temp. | Desiccate at RT |
|---|---|
| solubility | Soluble to 75 mM in DMSO and to 75 mM in ethanol |
| form | solid |
| color | off-white |
| FDA UNII | Q77EAZ9TG9 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305+P351+P338 |
| WGK Germany | 3 |
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L3169 | LP 12 hydrochloride hydrate ≥98% (HPLC), solid | 1185136-22-4 | 10mg | $206 | 2024-03-01 | Buy |
| Sigma-Aldrich | L3169 | LP 12 hydrochloride hydrate ≥98% (HPLC), solid | 1185136-22-4 | 50mg | $840 | 2023-01-07 | Buy |
| TRC | L473203 | LP12Hydrochloride | 1185136-22-4 | 5mg | $330 | 2021-12-16 | Buy |
| TRC | L473203 | LP12Hydrochloride | 1185136-22-4 | 2.5mg | $195 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000033 | LP 12 HYDROCHLORIDE HYDRATE 95.00% | 1185136-22-4 | 10MG | $695.51 | 2021-12-16 | Buy |
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride Chemical Properties,Uses,Production
Uses
LP 12 Hydrochloride is a 5-HT7 agonist.
Biological Activity
LP 12 dihydrochloride is a 5-HT7 receptor agonist displaying selectivity over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.13, 224, 60.9 and 1464 nM, respectively. It also displays selectivity over D2, 1723; over 5-HT1A, 468; over 5-HT2A, 11261; and high potency. Sigma has added LP 44 (L9793) which shows significantly lower D2 selectivity (7.3 nM/0.22 nM for 33-fold), lower selectivity over 5-HT1A, 240; and over 5-HT2A, 1482. LP 12 and LP 44 seem to share a common intermediate.
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| EMMX Biotechnology LLC | 60 |
| BOC Sciences | 65 |
LP 12 hydrochloride
LP 12 hydrochloride hydrate
6-(4-([1,1'-Biphenyl]-2-yl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
4-(2-Diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamidehydrochloride
LP-12 hydrochloride, 5-HT7 agonist
1185136-22-4
C32H39N30HCl
C32H39N3O