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17-phenyl trinor Prostaglandin E2 ethyl amide

17-phenyl trinor Prostaglandin E2 ethyl amide Structure
17-phenyl trinor Prostaglandin E2 ethyl amide structure
CAS No.
1219032-20-8
Chemical Name:
17-phenyl trinor Prostaglandin E2 ethyl amide
Synonyms
17-phenyl trinor Prostaglandin E2 ethyl amide;17-phenyl trinor Prostaglandin E2 ethyl amide Exclusive;(Z)-N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide;5-Heptenamide, N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-, (5Z)-
CBNumber:
CB32589942
Molecular Formula:
C25H35NO4
Molecular Weight:
413.55
MDL Number:
MOL File:
1219032-20-8.mol
Last updated:2025-04-18 09:52:04
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17-phenyl trinor Prostaglandin E2 ethyl amide Properties

Boiling point 629.4±55.0 °C(Predicted)
Density 1.141±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka 13.78±0.60(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H225-H319-H360
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P308+P313-P337+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
2 0

17-phenyl trinor Prostaglandin E2 ethyl amide price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13532 17-phenyl trinor Prostaglandin E2 ethyl amide ≥98% 1219032-20-8 1mg $94 2024-03-01 Buy
Cayman Chemical 13532 17-phenyl trinor Prostaglandin E2 ethyl amide ≥98% 1219032-20-8 5mg $418 2024-03-01 Buy
Cayman Chemical 13532 17-phenyl trinor Prostaglandin E2 ethyl amide ≥98% 1219032-20-8 10mg $739 2024-03-01 Buy
AK Scientific 0692DJ (Z)-N-Ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide 1219032-20-8 5mg $561 2021-12-16 Buy
Product number Packaging Price Buy
13532 1mg $94 Buy
13532 5mg $418 Buy
13532 10mg $739 Buy
0692DJ 5mg $561 Buy

17-phenyl trinor Prostaglandin E2 ethyl amide Chemical Properties,Uses,Production

Uses

17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis[1].

in vivo

17-Phenyl trinor prostaglandin E2 ethyl amide (0.3 μg/g; i.p.; three times a week for 12 weeks) aggravates renal dysfunction and glomerulosclerosis in five?sixths nephrectomy renal fibrosis model mice[1].

Animal Model:8-12 weeks, 15-20 g, C57/BL6 male mice (five?sixths nephrectomy renal fibrosis model)[1]
Dosage:0.3 μg/g
Administration:I.p.; three times a week for 12 weeks
Result:Increased the plasma blood urea nitrogen (BUN) levels and plasma creatinine (Cr) concentration, increased the extracellular matrix and the area of collagen deposition, upregulated the protein of expression of Col1, GRP78, TRPC1 and PERK in 5/6 Nx mice.

References

[1] Chen X, et al. Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis. Mol Med Rep. 2020 Oct;22(4):2887-2895. DOI:10.3892/mmr.2020.11353

17-phenyl trinor Prostaglandin E2 ethyl amide Preparation Products And Raw materials

Raw materials

Preparation Products

17-phenyl trinor Prostaglandin E2 ethyl amide Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1990 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24642 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 27736 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
BOC Sciences 65
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Cayman Chemical Company 58

View Lastest Price from 17-phenyl trinor Prostaglandin E2 ethyl amide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
17-phenyl trinor Prostaglandin E2 ethyl amide pictures 2024-10-28 17-phenyl trinor Prostaglandin E2 ethyl amide
1219032-20-8
 US $987.00-235.00 / mg 10g TargetMol Chemicals Inc.
17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor Prostaglandin E2 ethyl amide Exclusive (Z)-N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide 5-Heptenamide, N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-, (5Z)- 1219032-20-8