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Auristatin E

Auristatin E structure

CAS No.: 160800-57-7

Chemical Name:: Auristatin E

Synonyms: Auristatin E;Auristatin E,inhibit,ADC Payload,ADC Cytotoxin,Inhibitor,Microtubule/Tubulin;L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;(2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide;(S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide

CBNumber:: CB32667365

Molecular Formula:: C40H69N5O7

Molecular Weight:: 732.01

MDL Number:: MFCD25976744

MOL File:: 160800-57-7.mol

Last updated:2024-11-01 15:07:50

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Auristatin E Properties

Melting point	92-94 °C
Boiling point	871.0±65.0 °C(Predicted)
Density	1.085±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C,unstable in solution, ready to use.
solubility	Soluble in DMSO
form	Solid
pka	13.66±0.20(Predicted)
color	White to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H341-H361-H372
Precautionary statements	P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501-P260-P264-P270-P314-P501

Auristatin E price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-3435	AuristatinE 99.36%	160800-57-7	1mg	$150	2021-12-16	Buy
ChemScene	CS-3435	AuristatinE 99.36%	160800-57-7	5mg	$440	2021-12-16	Buy
ChemScene	CS-3435	AuristatinE 99.36%	160800-57-7	10mg	$740	2021-12-16	Buy
BroadPharm	BP-23645	AuristatinE 95%	160800-57-7	50mg	$1300	2021-12-16	Buy
DC Chemicals	DC10138	AuristatinE >98%	160800-57-7	250mg	$1800	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-3435	1mg	$150	Buy
CS-3435	5mg	$440	Buy
CS-3435	10mg	$740	Buy
BP-23645	50mg	$1300	Buy
DC10138	250mg	$1800	Buy

Auristatin E Chemical Properties,Uses,Production

Description

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent. Auristatin E inhibits tubulin polymerization(1). Auristatin E-antibody cunjugates have proven to be successful anticancer agents.(2)
Ref. 1. Pettit et al. Anticancer Drug Des. 1995 10:529.
Ref. 2. Doronina et al. Nature Biotechnol. 2003 21:778.

Auristatin E Preparation Products And Raw materials

Raw materials

Preparation Products

Auristatin E Suppliers

Global( 77)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9218	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Jurong Coupling Biotechnology Co., Ltd.	13656108824	coupling278191416@hotmail.com	CHINA	184	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32070	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9315	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
Zhuoer Chemical Co., Ltd	02120970332; +8613524231522	sales@zhuoerchem.com	China	2904	58

Supplier	Advantage
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
BOC Sciences	58
Jurong Coupling Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Baoji Guokang Bio-Technology Co., Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Zhuoer Chemical Co., Ltd	58

View Lastest Price from Auristatin E manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-01	Auristatin E 160800-57-7	US $44.00-29.00 / mg		98.81%	10g	TargetMol Chemicals Inc.
2024-11-01	Auristatin E 160800-57-7	US $44.00-29.00 / mg		98.81%	10g	TargetMol Chemicals Inc.
2021-09-16	Auristatin E 160800-57-7	US $0.00-0.00 / KG	1g	99%	100KG	Hangzhou Huarong Pharm Co., Ltd.

Auristatin E
160800-57-7
US $44.00-29.00 / mg
98.81%
TargetMol Chemicals Inc.

Auristatin E
160800-57-7
US $44.00-29.00 / mg
98.81%
TargetMol Chemicals Inc.

Auristatin E
160800-57-7
US $0.00-0.00 / KG
99%
Hangzhou Huarong Pharm Co., Ltd.

160800-57-7(Auristatin E)Related Search:

Auristatin F Ozone Feed Mould inhibitor

Auristatin E L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl- Auristatin E,inhibit,ADC Payload,ADC Cytotoxin,Inhibitor,Microtubule/Tubulin (S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide (2S)-2-[(2S)-2-(dimethylamino)-3-methylbutanamido]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide 160800-57-7 160800-57-8 C40H69N5O7