UNC0379 (trifluoroacetate)
- CAS No.
- 1620401-83-3
- Chemical Name:
- UNC0379 (trifluoroacetate)
- Synonyms
- UNC0379 TFA;UNC0379 (trifluoroacetate);UNC0379 trifluoroacetate salt;UNC0379 trifluoroacetate salt >=98% (HPLC)
- CBNumber:
- CB32735543
- Molecular Formula:
- C25H36F3N5O4
- Molecular Weight:
- 527.59
- MDL Number:
- MOL File:
- 1620401-83-3.mol
UNC0379 (trifluoroacetate) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-3606 | UNC0379TFA 99.91% | 1620401-83-3 | 2mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-3606 | UNC0379TFA 99.91% | 1620401-83-3 | 5mg | $120 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611655 | UNC0379 trifluoroacetate | 1620401-83-3 | 100mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611655 | UNC0379 trifluoroacetate | 1620401-83-3 | 250mg | $1504.5 | 2021-12-16 | Buy |
| DC Chemicals | DC23217 | UNC0379trifluoroacetate >98% | 1620401-83-3 | 1g | $2000 | 2021-12-16 | Buy |
UNC0379 (trifluoroacetate) Chemical Properties,Uses,Production
Biological Activity
SETD8 expression is observed in cancers such as bladder cancer, chronic myelogenous leukemia, hepatocellular carcinoma, non‐small‐cell lung carcinoma, prostate cancer, small‐cell lung carcinoma. Therefore inhibition of SETD8 (SET‐domain containing protein) by UNC0379 might prevent the progression of cancer.', 'UNC0379 is the first substrate-competitive inhibitor of the lysine methyltransferase SETD8, the only known methyltransferase th at catalyzes monomethylation of histone H4 lysine 20 (H4K20). HK420 methylation has been implicated in the regulation of a variety of biological processes including the DNA damage response. UNC0379 is selective for SETD8 over 15 other methyltransferases, with an IC50 value of 7.3 μM for SETD8 compared to IC50 vlaues over 100 μM for other methyltransferases.
UNC0379 (trifluoroacetate) Preparation Products And Raw materials
Raw materials
Preparation Products
UNC0379 (trifluoroacetate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3866 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9409 | 58 |