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Entacapone EP Impurity G
- CAS No.
- 1364322-41-7
- Chemical Name:
- Entacapone EP Impurity G
- Synonyms
- Entacapone EP Impurity G;N,N-Bis-desethyl, N-Methyl Entacapone;(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide;2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-, (2E)-;(E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide (Entacapone Impurity)
- CBNumber:
- CB32741801
- Molecular Formula:
- C11H9N3O5
- Molecular Weight:
- 263.21
- MDL Number:
- MOL File:
- 1364322-41-7.mol
- MSDS File:
- SDS
Last updated:2022-12-21 16:56:50
Boiling point | 544.6±50.0 °C(Predicted) |
---|---|
Density | 1.537±0.06 g/cm3(Predicted) |
pka | 4.88±0.50(Predicted) |
FDA UNII | 31599TJ137 |
Entacapone EP Impurity G Chemical Properties,Uses,Production
Uses
N,N-Bis-desethyl, N-Methyl Entacapone is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
Entacapone EP Impurity G Preparation Products And Raw materials
Raw materials
Preparation Products
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Entacapone EP Impurity G
N,N-Bis-desethyl, N-Methyl Entacapone
2-Propenamide, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methyl-, (2E)-
(E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide (Entacapone Impurity)
(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N-methylacrylamide
1364322-41-7