Anti-Nuclear factor, erythroid derived 2
- CAS No.
- Chemical Name:
- Anti-Nuclear factor, erythroid derived 2
- Synonyms
- Anti-NFE2-related factor 2;Anti-NFE2L2 antibody produced in rabbit;Anti-Nuclear factor, erythroid derived 2
- CBNumber:
- CB32883255
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317-H412 |
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 |
Anti-Nuclear factor, erythroid derived 2 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB2701989 | Anti-NFE2L2 antibody produced in rabbit | 100μL | $467 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA043438 | Anti-NFE2L2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 25μL | $282 | 2023-06-20 | Buy | |
| Sigma-Aldrich | HPA043438 | Anti-NFE2L2 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody | 100μL | $547 | 2023-06-20 | Buy |
Anti-Nuclear factor, erythroid derived 2 Chemical Properties,Uses,Production
Uses
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:500-1:3000, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
General Description
The nuclear factor erythroid 2-related factor 2 (NFE2L2) is a major transcriptional factor. NRF2 gene codes for NFE2L2. It is a member of the cap ‘n′ collar (Cnc) family of basic leucine zipper transcription factors. It is located on human chromosome 2q31.
Biochem/physiol Actions
NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]The nuclear factor erythroid 2-related factor 2 (Nrf2) controls phase II detoxifying enzymes, antioxidants and efflux transporters like P-glycoprotein (P-gp). De novo mutations in NFE2L2 results in a multisystem disorder. It modulates the expression of more than 200 genes.
Anti-Nuclear factor, erythroid derived 2 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Nuclear factor, erythroid derived 2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Merck Millipore | 1-400-889-1988 400-889-1988 | bioscience@merckgroup.com | China | 59839 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 292394 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Merck Millipore | 58 |
| Merck KGaA | 58 |