ChemicalBook >> CAS DataBase List >>BC 11-38
BC 11-38
- CAS No.
- 686770-80-9
- Chemical Name:
- BC 11-38
- Synonyms
- 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one;3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-;cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138
- CBNumber:
- CB33037165
- Molecular Formula:
- C15H16N2OS2
- Molecular Weight:
- 304.43
- MDL Number:
- MOL File:
- 686770-80-9.mol
Last updated:2023-05-18 11:31:06
BC 11-38 price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 20167 | BC-11-38 ≥98% | 686770-80-9 | 5mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 20167 | BC-11-38 ≥98% | 686770-80-9 | 10mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 20167 | BC-11-38 ≥98% | 686770-80-9 | 25mg | $252 | 2024-03-01 | Buy |
TRC | B129345 | BC11-38 | 686770-80-9 | 25mg | $285 | 2021-12-16 | Buy |
ApexBio Technology | B7673 | BC11-38 | 686770-80-9 | 10mg | $291 | 2021-12-16 | Buy |
BC 11-38 Chemical Properties,Uses,Production
Description
BC-11-38 (686770-80-9) is a? potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1? IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2
Uses
BC 11-38 is a selective inhibitor of phosphodiesterase 11. Potent PDE-11 inhibitor
References
1) Ceyhan et al. (2012), Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen; Chem. Biol., 19 155 2) Lu and Sewer (2015), p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation; Mol. Cell. Biol. 35 1223
BC 11-38 Preparation Products And Raw materials
Raw materials
Preparation Products
BC 11-38 Suppliers
Global( 28)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 4182 | 55 |
Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
686770-80-9(BC 11-38)Related Search:
3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one
Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-
cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138
686770-80-9