Selank peptide
- CAS No.
- 129954-34-3
- Chemical Name:
- Selank peptide
- Synonyms
- SLANK;Selanc;SELANK;PL14736;Selank CAS;Salbu Sulfate;Selank peptid;SelankAcetate;Selankamidate;Selank peptide
- CBNumber:
- CB33161651
- Molecular Formula:
- C33H57N11O9
- Molecular Weight:
- 751.87
- MDL Number:
- MFCD11840762
- MOL File:
- 129954-34-3.mol
| Melting point | 134-136 °C |
|---|---|
| Density | 1.53±0.1 g/cm3(Predicted) |
| pka | 3.43±0.20(Predicted) |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| InChIKey | JTDTXGMXNXBGBZ-YVHUGQOKSA-N |
| SMILES | C(O)(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)N |
| FDA UNII | TS9JR8EP1G |
Selank peptide price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 5mg | $508 | 2023-01-06 | Buy |
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 10mg | $879 | 2023-01-06 | Buy |
| Cayman Chemical | 27720 | Selank (acetate) | 129954-34-3 | 1mg | $136 | 2023-01-06 | Buy |
Selank peptide Chemical Properties,Uses,Production
Description
Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.
Uses
Selank peptide has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. It is often prescribed for its anxiolytic properties, immune improvement, gastric protection, and with opioid and alcohol withdrawal/ dependence. It also has a nootropic action, which positively influences the formation of memory and learning processes, and marked immunomodulatory activity.
benefits
Selank peptide has the following benefits: It improves anxiety and stress reactions. Enhances memory and learning. Strengthens immune function by increasing inflammatory proteins to help fight infections. Increases BDNF (brain-derived neurotrophicfactor) - a vital brain-growth compoundrelated to learning and memory. Prevent weight gain and reduce cholesterol. Decreases alcohol-withdrawal-related anxiety. Decreased blood pressure and increased brain blood flow. Helps to increase lymph flow to the stomach and decrease stomach ulcers. Stabilizes blood enkephalins - natural peptides that can reduce stress.
Mechanism of action
Selank peptide is known that the classical benzodiazepines act via gamma-aminobutyric acid (GABA) type A receptors. They enhance the GABA effect by allosteric modulation, which increases the frequency of opening of channels for chlorine ions. The Selank action mechanism may be related to its ability to affect the performance of the GABAergic system.
Side effects
These are the possible side effects:
Anxiety
Headaches
Nausea
Dizziness
Fatigue
Selank peptide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Soarwin Technology Co., Ltd | +86-19132938950 +86-19132938950 | crystal@sorawin.cn | China | 360 | 58 |
| .GZ HONESTCHEM CO.,LTD | +86-15013270415 +86-15013270415 | honestchemical@foxmail.com | China | 246 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49984 | 58 |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3512 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 | admin@86-ss.com | China | 1001 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +8617709210191 | Jerry@xhobio.com | China | 884 | 58 |
| Anko Intermational Trade Limited | +86-18073326374 +86-18073326374 | sales@goodpeptides.com | China | 58 | 58 |
| Forest chemical technology | +85295407470 | grant@forestchem.freeqiye.com | China | 737 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
Related articles
- Efficacy and side effects of Selank peptide anti-anxiety
- Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic mild, highly effective antianxiety peptide drug that can be used to treat ....
- Jan 15，2025
- The benefits of Selank peptide
- Selank peptide is efficient in promoting relaxation and reducing anxiety and depression by correcting the serotonin metabolism....
- Jun 5，2024
View Lastest Price from Selank peptide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-26 | Selank peptide
129954-34-3
|
US $1.00 / g | 1g | 99% | 100kg | RongNa Biotechnology Co.,Ltd | |
 |
2025-04-25 | Selank
129954-34-3
|
US $4.00-60.00 / mg | 5mg | 99% HPLC | 20kg | Anko Intermational Trade Limited | |
 |
2025-04-25 | Selank peptide
129954-34-3
|
US $0.00 / g | 1g | 99% | 100G | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- Selank peptide
129954-34-3
- US $1.00 / g
- 99%
- RongNa Biotechnology Co.,Ltd
-
- Selank
129954-34-3
- US $4.00-60.00 / mg
- 99% HPLC
- Anko Intermational Trade Limited
-
- Selank peptide
129954-34-3
- US $0.00 / g
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD