1,1,1-Trifluoroethyl-PEG2-azide
- CAS No.
- 1835759-68-6
- Chemical Name:
- 1,1,1-Trifluoroethyl-PEG2-azide
- Synonyms
- 1,1,1-Trifluoroethyl-PEG2-azide
- CBNumber:
- CB33162799
- Molecular Formula:
- C6H10F3N3O2
- Molecular Weight:
- 213.16
- MDL Number:
- MFCD29042341
- MOL File:
- 1835759-68-6.mol
1,1,1-Trifluoroethyl-PEG2-azide price
1,1,1-Trifluoroethyl-PEG2-azide Chemical Properties,Uses,Production
Description
1,1,1-Trifluoroethyl-PEG2-azide is a crosslinker containing an azide group and a trifluroethyl group. The azide group can participate in Click Chemistry reactions with reagents such as alkynes, DBCO and BCN. The hydrophilic PEG spacer increases solubility in aqueous media. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.
Uses
1,1,1-Trifluoroethyl-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1,1,1-Trifluoroethyl-PEG2-azide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32239 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38648 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-0431-80514535 19917294565 | et@chemextension.com | China | 3962 | 55 |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55017 | 58 |
View Lastest Price from 1,1,1-Trifluoroethyl-PEG2-azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-30 | 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
|
US $48.00-34.00 / mg | 96.06% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-27 | 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
|
US $0.00 / mg | 500mg | >98.00% | 500mg | Xian confluore Biological Technology Co., Ltd. |
-
- 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
- US $48.00-34.00 / mg
- 96.06%
- TargetMol Chemicals Inc.
-
- 1,1,1-Trifluoroethyl-PEG2-azide
1835759-68-6
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.