Duloxetine-d3 hydrochloride
- CAS No.
- 1188266-11-6
- Chemical Name:
- Duloxetine-d3 hydrochloride
- Synonyms
- 2H3]-Duloxetine HCl;rac-Duloxetine-d3 HCl;Duloxetine-d3 hydrochloride;rac-Duloxetine-d3 Hydrochloride;N-(methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine,monohydrochloride
- CBNumber:
- CB33163408
- Molecular Formula:
- C18H20ClNOS
- Molecular Weight:
- 333.87
- MDL Number:
- MOL File:
- 1188266-11-6.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
NFPA 704 |
|
Duloxetine-d3 hydrochloride price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25229 | Duloxetine-d3 (hydrochloride) ≥99% deuterated forms (d1-d3) | 1188266-11-6 | 1mg | $194 | 2024-03-01 | Buy |
AK Scientific | 8728DF | 3-Naphthalen-1-yloxy-3-thiophen-2-yl-N-(trideuteriomethyl)propan-1-amine;hydrochloride | 1188266-11-6 | 1mg | $314 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006792 | DULOXETINE-D3 HYDROCHLORIDE 95.00% | 1188266-11-6 | 5MG | $1424.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006792 | DULOXETINE-D3 HYDROCHLORIDE 95.00% | 1188266-11-6 | 25MG | $3150 | 2021-12-16 | Buy |
Duloxetine-d3 hydrochloride Chemical Properties,Uses,Production
Description
Duloxetine-d3 is intended for use as an internal standard for the quantification of duloxetine by GC- or LC-MS. (S)-Duloxetine is a potent inhibitor of serotonin and norepinephrine reuptake (Kis = 4.6 and 15.6 nM, respectively, for rat synaptosomes). It also inhibits dopamine reuptake (Ki = 369 nM). (S)-Duloxetine suppresses spontaneous firing activity in vivo in the dorsal raphe and locus coeruleus (ED50s = 99 and 475 μg/kg, respectively). It also decreases immobility time and increases latency to first immobility in the forced swim test in mice when administered at doses of 16 and 32 mg/kg. Formulations containing (S)-duloxetine have been used in the treatment of major depressive disorder, generalized anxiety disorder, chronic neuropathic and musculoskeletal pain, and fibromyalgia.
Duloxetine-d3 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Duloxetine-d3 hydrochloride Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 7176 | 65 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18018 | 56 |
Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 2754 | 58 |
Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2276 | 58 |
Hefei Molake Biotechnology Co., Ltd. | 0551-66336380 18956014586 | 983438788@qq.com | China | 2103 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | info@synzest.com | China | 9287 | 58 |
PureChemland Co.,Ltd. | 19150123681 | 3848291069@qq.com | China | 3242 | 58 |
Shanghai isotope chemical co.,ltd | 021-021-51600108 13062666369 | sales@chinaisotope.com | China | 4274 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |