Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)
![Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Structure](CAS/20180528/GIF/111112-18-6.gif)
- CAS No.
- 111112-18-6
- Chemical Name:
- Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)
- Synonyms
- LY195448 HCl;UNII-BR0DFE3GF6;Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)
- CBNumber:
- CB33178840
- Molecular Formula:
- C20H27ClN2O2
- Molecular Weight:
- 362.9
- MDL Number:
- MOL File:
- 111112-18-6.mol
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Properties
| FDA UNII | BR0DFE3GF6 |
|---|
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Chemical Properties,Uses,Production
Uses
LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of "standard" side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor.
References
[1] Phase I clinical and pharmacokinetic study of LY 195448
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19710 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | LY195448 HCl
111112-18-6
|
US $2500.00-1980.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- LY195448 HCl
111112-18-6
- US $2500.00-1980.00 / mg
- TargetMol Chemicals Inc.