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N,N'-Disuccinimidyl carbonate

CAS No.
74124-79-1
Chemical Name:
N,N'-Disuccinimidyl carbonate
Synonyms
DSC;Bis(2,5-dioxopyrrolidin-1-yl) carbonate;DISUCCINIMIDYL CARBONATE;SU2O;DI(SUCCINIMIDO) CARBONATE;DI(N-SUCCINIMIDYL) CARBONATE;BIS(N-SUCCINIMIDYL) CARBONATE;Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester;(SUO)2CO;DSCsee24500
CBNumber:
CB3323388
Molecular Formula:
C9H8N2O7
Molecular Weight:
256.17
MDL Number:
MFCD00009767
MOL File:
74124-79-1.mol
MSDS File:
SDS
Last updated:2023-08-22 13:52:55

N,N'-Disuccinimidyl carbonate Properties

Melting point 190 °C (dec.)(lit.)
Boiling point 399.41°C (rough estimate)
Density 1.5670 (rough estimate)
refractive index 1.5600 (estimate)
storage temp. -20°C
solubility Dichloromethane (Slightly, Heated), DMSO
form Crystalline Powder
color White to slightly yellow
Water Solubility Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water.
BRN 1499137
Stability Moisture Sensitive
InChIKey PFYXSUNOLOJMDX-UHFFFAOYSA-N
CAS DataBase Reference 74124-79-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H319-H373
Precautionary statements  P260-P264-P270-P301+P312-P305+P351+P338-P314
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-37/39-36
WGK Germany  3
10-21
TSCA  No
HS Code  29299000
NFPA 704
0
2 1

N,N'-Disuccinimidyl carbonate price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.51005 DSC N,N′-Disuccinimidyl carbonate Novabiochem? 74124-79-1 25g $222 2024-03-01 Buy
Sigma-Aldrich 8.51005 DSC N,N′-Disuccinimidyl carbonate Novabiochem? 74124-79-1 100g $660 2024-03-01 Buy
Sigma-Aldrich 8.14971 Di-(N,N′-succinimidyl) carbonate for synthesis 74124-79-1 5G $172 2024-03-01 Buy
Sigma-Aldrich 225827 N,N′-Disuccinimidyl carbonate ≥95% 74124-79-1 1g $25.74 2024-03-01 Buy
Sigma-Aldrich 225827 N,N′-Disuccinimidyl carbonate ≥95% 74124-79-1 5g $111 2024-03-01 Buy
Product number Packaging Price Buy
8.51005 25g $222 Buy
8.51005 100g $660 Buy
8.14971 5G $172 Buy
225827 1g $25.74 Buy
225827 5g $111 Buy

N,N'-Disuccinimidyl carbonate Chemical Properties,Uses,Production

Chemical Properties

N,N'-Disuccinimidyl carbonate is white to slightly yellow crystalline powder

Uses

N,N'-Disuccinimidyl carbonate is a convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids.

Uses

N,N’Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of lig ands to proteins. The coupling reagent property of N,N’Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity.

Uses

N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.

Synthesis Reference(s)

Tetrahedron Letters, 20, p. 4745, 1979 DOI: 10.1016/S0040-4039(01)86699-5

General Description

N,N′-Disuccinimidyl carbonate is used for the HPLC determination of amino compounds.

Global( 552)Suppliers
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Hebei Mojin Biotechnology Co., Ltd
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Capot Chemical Co.,Ltd.
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323-480-4688 sales@acrospharmatech.com United States 989 55
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career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29882 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58

View Lastest Price from N,N'-Disuccinimidyl carbonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N'-Disuccinimidyl carbonate pictures 2024-11-14 N,N'-Disuccinimidyl carbonate
74124-79-1
US $115.00 / KG 1KG 98% 1-10mt Baoji Guokang Bio-Technology Co., Ltd.
N,N'-Disuccinimidyl carbonate pictures 2023-08-22 N,N'-Disuccinimidyl carbonate
74124-79-1
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
N,N'-Disuccinimidyl carbonate pictures 2022-09-27 N,N'-Disuccinimidyl carbonate
74124-79-1
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
2,5-PYRROLIDINEDIONE, 1,1'-[CARBONYLBIS(OXY)]BIS- di-N,N'-succnimidly carbonat N,Nzzhlxy-Disuccinimidyl carbonate (DSC) Carbonic acid, bis(2,5-dioxo-1-pyrrolidinyl) ester N-Succinimidyl Carbonate N,N'-Disuccinimidyl Carbonate DSC DI-(N,N'-SUCCINIMIDYL) CARBONATE FOR SYN N,N-DisucciniMdyl carbonate Bis(2,5-dioxopyrrolidin-1-yl) carbonate 98% N,N'-Disuccinimidyl carbonate, DSC, 1,1'-[Carbonylbis(oxy)]dipyrrolidine-2,5-dione N,N'-DisucciniMidyl carbonate >=95% N,N'-DisucciniMidyl carbonate puruM, >=95.0% (NMR) N,N′-Disuccinimidyl carbonate N,N'-DISUCCINIMIDYL CARBONATE, TECH. DSC [N,N'-DISUCCINIMIDYL CARBONATE] N,N'-Disuccinimidyl carbonate (DSC) N,N'-DisuccinimidylCarbonate98% N,N'-Disuccinimido Carbonate DSCsee24500 N,N'-Disuccinimidyl N,N'-Disuccinimidyl carbonate, tech. 85%, remainder N-hydroxysuccinimide N-Succinimidyl carbonate, Di(N-succinimidyl) carbonate, DSC N,N'-Disuccinimidyl carbonate ,99% 1,1'-(Carbonylbisoxy)bis(pyrrolidine-2,5-dione) 1,1'-[Carbonylbis(oxy)]bis(2,5-pyrrolidinedione) Carbonic acid bis(succinimidyl) ester N,N'-(Carbonylbisoxy)bissuccinimide DSC (Di(N-succinimidyl)carbonate 1,1''-[CARBONYLBIS(OXY)]DIPYRROLIDINE-2,5-DIONE Disuccinimidyl carbonate, Su2O DSC (Di(N-succinimidyl)carbonate: N-Succinimidyl carbonate) N,N'-Disuccinimidyl carbonate≥ 99% (HPLC) DSC N,N'-Disuccinimidyl carbonate Novabiochem Di-(N,N'-succinimidyl) carbonate for synthesis TIMTEC-BB SBB005976 (SUO)2CO DI-(N,N'-SUCCINIMIDYL) CARBONATE LABOTEST-BB LT00847311 N-SUCCINIMIDYL CARBONATE N,N'-DISUCCINIMIDYL CARBONATE N'-Disuccinimidyl carbonate Di(N-succinimidyl)Carbonate> N,N''-Disuccinimidyl carbonate, Tech Grade N,N'-Disuccinimidyl carbonate USP/EP/BP N,N′-Disuccinimidyl Carbonate (Technical Grade) Di-(N-Succinimidyl) Carbonate extrapure, 95% Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester Bis(2,5-dioxopyrrolidin-1-yl) carbonate SU2O BIS(N-SUCCINIMIDYL) CARBONATE DSC DI(SUCCINIMIDO) CARBONATE DISUCCINIMIDYL CARBONATE DI(N-SUCCINIMIDYL) CARBONATE N. N '- Disuccinimide carbonate N,N' -dissuccinimide carbonate N,N'-Disuccinimidyl carbonate DSCN,N'-Disuccinimidyl carbonate 74124-79-1