N,N'-Disuccinimidyl carbonate
- CAS No.
- 74124-79-1
- Chemical Name:
- N,N'-Disuccinimidyl carbonate
- Synonyms
- DSC;Bis(2,5-dioxopyrrolidin-1-yl) carbonate;DISUCCINIMIDYL CARBONATE;SU2O;DI(SUCCINIMIDO) CARBONATE;DI(N-SUCCINIMIDYL) CARBONATE;BIS(N-SUCCINIMIDYL) CARBONATE;Carbonic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester;(SUO)2CO;DSCsee24500
- CBNumber:
- CB3323388
- Molecular Formula:
- C9H8N2O7
- Molecular Weight:
- 256.17
- MDL Number:
- MFCD00009767
- MOL File:
- 74124-79-1.mol
- MSDS File:
- SDS
Melting point | 190 °C (dec.)(lit.) |
---|---|
Boiling point | 399.41°C (rough estimate) |
Density | 1.5670 (rough estimate) |
refractive index | 1.5600 (estimate) |
storage temp. | -20°C |
solubility | Dichloromethane (Slightly, Heated), DMSO |
form | Crystalline Powder |
color | White to slightly yellow |
Water Solubility | Soluble in dimethyl sulfoxide, hot pyridine, acetonitrile and most organic solvents. Insoluble in water. |
BRN | 1499137 |
Stability | Moisture Sensitive |
InChIKey | PFYXSUNOLOJMDX-UHFFFAOYSA-N |
CAS DataBase Reference | 74124-79-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H319-H373 | |||||||||
Precautionary statements | P260-P264-P270-P301+P312-P305+P351+P338-P314 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-36/37/38 | |||||||||
Safety Statements | 26-37/39-36 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
TSCA | No | |||||||||
HS Code | 29299000 | |||||||||
NFPA 704 |
|
N,N'-Disuccinimidyl carbonate price More Price(66)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.51005 | DSC N,N′-Disuccinimidyl carbonate Novabiochem? | 74124-79-1 | 25g | $222 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.51005 | DSC N,N′-Disuccinimidyl carbonate Novabiochem? | 74124-79-1 | 100g | $660 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.14971 | Di-(N,N′-succinimidyl) carbonate for synthesis | 74124-79-1 | 5G | $172 | 2024-03-01 | Buy |
Sigma-Aldrich | 225827 | N,N′-Disuccinimidyl carbonate ≥95% | 74124-79-1 | 1g | $25.74 | 2024-03-01 | Buy |
Sigma-Aldrich | 225827 | N,N′-Disuccinimidyl carbonate ≥95% | 74124-79-1 | 5g | $111 | 2024-03-01 | Buy |
N,N'-Disuccinimidyl carbonate Chemical Properties,Uses,Production
Chemical Properties
N,N'-Disuccinimidyl carbonate is white to slightly yellow crystalline powder
Uses
N,N'-Disuccinimidyl carbonate is a convenient reagent for the synthesis of N-succinimidyl esters of N-protected amino acids.
Uses
N,N’Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of lig ands to proteins. The coupling reagent property of N,N’Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity.
Uses
N,N'-Disuccinimidyl carbonate is used to prepare cleavable linker succinimide vinylsufonylethyl carbonate for thiol modified-DNA. It serves as a reagent for the synthesis of carbamates. Further, it is used as a coupling reagent as well as in the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate and coupling of ligand to proteins.
Synthesis Reference(s)
Tetrahedron Letters, 20, p. 4745, 1979 DOI: 10.1016/S0040-4039(01)86699-5
General Description
N,N′-Disuccinimidyl carbonate is used for the HPLC determination of amino compounds.
N,N'-Disuccinimidyl carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9210 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
View Lastest Price from N,N'-Disuccinimidyl carbonate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-14 | N,N'-Disuccinimidyl carbonate
74124-79-1
|
US $115.00 / KG | 1KG | 98% | 1-10mt | Baoji Guokang Bio-Technology Co., Ltd. | ||
2023-08-22 | N,N'-Disuccinimidyl carbonate
74124-79-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2022-09-27 | N,N'-Disuccinimidyl carbonate
74124-79-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
- N,N'-Disuccinimidyl carbonate
74124-79-1
- US $115.00 / KG
- 98%
- Baoji Guokang Bio-Technology Co., Ltd.
- N,N'-Disuccinimidyl carbonate
74124-79-1
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- N,N'-Disuccinimidyl carbonate
74124-79-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.