ChemicalBook >> CAS DataBase List >>4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE

CAS No.
94-19-9
Chemical Name:
4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE
Synonyms
setd;etazol;etazole;globucid;ethazole;globucin;globuzid;sethadil;aethazol;berlophen
CBNumber:
CB3325377
Molecular Formula:
C10H12N4O2S2
Molecular Weight:
284.36
MDL Number:
MFCD00057224
MOL File:
94-19-9.mol
Last updated:2023-05-04 17:34:43

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Properties

Melting point 185.5-186.0°
Density 1.3410 (rough estimate)
refractive index 1.6440 (estimate)
pka pKa 5.36(H2O t = 37) (Uncertain)
Water Solubility 215mg/L(20 ºC)
FDA UNII R77Q4O5ZMD

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H302-H335-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
HazardClass  IRRITANT
Toxicity LD50 intraperitoneal in mouse: 1459mg/kg

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 008104 4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide 94-19-9 1g $305 2021-12-16 Buy
AK Scientific 3860AF 4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide 94-19-9 1g $461 2021-12-16 Buy
American Custom Chemicals Corporation CHM0165391 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE 98.00% 94-19-9 500MG $762.3 2021-12-16 Buy
Aronis compounds BBC/507 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide 94-19-9 10g $501 2021-12-16 Buy
Aronis compounds BBC/507 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide 94-19-9 5g $371 2021-12-16 Buy
Product number Packaging Price Buy
008104 1g $305 Buy
3860AF 1g $461 Buy
CHM0165391 500MG $762.3 Buy
BBC/507 10g $501 Buy
BBC/507 5g $371 Buy

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Chemical Properties,Uses,Production

Originator

Sul-Spansion,SKF,US,1956

Definition

ChEBI: 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide is a member of benzenes and a sulfonamide.

Manufacturing Process

0.163 mol of 2-amino-5-ethyl-1,3,4-thiadiazole was covered with 43 parts of anhydrous pyridine. To the mixture was added 50 parts (0.214 mol) of pacetylaminobenzenesulfonyl chloride with vigorous shaking at 50°C to 60°C. The reaction mixture was then heated to 125°C. When the mixture had cooled somewhat it was placed in a Claisen flask and 27.6 parts (0.69 mol) of sodium hydroxide dissolved in 110 parts of water was added through a dropping funnel while distilling off a mixture of pyridine and water. The distillation was stopped when the temperature reached 100°C and the residual liquor in the flask heated at 95°C for 30 minutes.The reaction mixture was then poured into 1,650 parts of hot water, the pH adjusted to 8 to 9, decolorizing charcoal was added and the whole was heated on the steam for 15 minutes. The charcoal was filtered off and the hot filtrate neutralized and cooled. The 2-(sulfanilamido)-5-ethyl-1,3,4-thiadiazole was purified by repeated crystallization from boiling water.

Therapeutic Function

Antibacterial

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Suppliers

Global( 25)Suppliers
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Baoji Guokang Healthchem co.,ltd
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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
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ethazole(pharmaceutical) globucid sulfaethidol sulfaethidole sulfaethylthiadiazole sulfa-perlongit sul-spansion sul-spantab sulphaethidole Sulphanyl acid N-(5-ethyl-1,3,4-thiadiazol-2yl) amide 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE ethazole globucin globuzid n-(5-ethyl-1,3,4-thiadiazol-2-yl)-sulfanilamid n-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide setd sethadil sulfaethidiole TIMTEC-BB SBB001155 2-sulfanilamidoaethylthiodiazol 4-amino-n-(5-ethyl-1,3,4-thiadiazol-2-yl)-benzenesulfonamid aethazol berlophen etazol etazole 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzene-1-sulfonamide Benzenesulfonamide, 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)- 94-19-9 C10H12N4O2S2