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1-(3-Chlorophenyl)piperazine hydrochloride

CAS No.
65369-76-8
Chemical Name:
1-(3-Chlorophenyl)piperazine hydrochloride
Synonyms
M-CPP;1-(3-ChL;TIMTEC-BB SBB003261;M-CPP HYDROCHLORIDE;Trazodone Impurity 1;LABOTEST-BB LT00159902;TRAZODONE CPP IMPURITY;Aripiprazole Impurity 35;Aripiprazole Impurity 36;Trazodone Chlorophenylpiperazine
CBNumber:
CB3325544
Molecular Formula:
C10H14Cl2N2
Molecular Weight:
233.14
MDL Number:
MFCD00039032
MOL File:
65369-76-8.mol
Last updated:2023-04-23 13:52:06

1-(3-Chlorophenyl)piperazine hydrochloride Properties

Melting point 210-214 °C (dec.)(lit.)
Density 1,193g/cm
refractive index 1,598-1,600
Flash point 9℃
storage temp. Store at RT
solubility methanol: soluble
form Solid
color Pale brown
Stability Hygroscopic
CAS DataBase Reference 65369-76-8(CAS DataBase Reference)
FDA UNII 7IM2GS7ILV

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn,T,F
Risk Statements  36/37/38-22-39/23/24/25-23/24/25-11
Safety Statements  26-36-24/25-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
2 0

1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Off-white solid

Uses

Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.

General Description

1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Biological Activity

5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .

1-(3-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3-CHLOROPHENYL)PIPERAZINE 2HCL 1-(3-Chlorophenyl)piperazine hydrochloride,97% N-(3-Chlorophenyl) Piperazine HCl 1-(3-Chlorophenyl)piperazine hydrochloride 1-(3-CHLOROPHENYL)-PIPERAZINE HCL (MCLPPB) Piperazine, 1-(3-chlorophenyl)-, hydrochloride 1-(3-Chlorophenyl)piperidine/hydrochloric acid,(1:x) 1-(3-Chlorophenyl)piperazine hydrochloride ,98% 1-(3-Chlorophenyl)piperazine hydrochloride solution 1-(3-chlorophenyl)piperazine hydrochlori 1-(3-Chlorophenyl)piperazine (mCPP) HCl 1-(3-Chlorophenyl)piperazine hydrochloride 99% TIMTEC-BB SBB003261 N-(3-CHLOROPHENYL) PIPERAZINE HYDROCHLORIDE LABOTEST-BB LT00159902 M-CPP M-CPP HYDROCHLORIDE 1-(M-CHLOROPHENYL) PIPERAZINE HYDROCHLORIDE 1-(3-CHLORO PHENYL)-PIPERAZINE HCL 1-(3-CHLOROPHENYL)PIPERAZINE MONOHYDROCHLORIDE 1-(3-Chlorophenyl)piperazine hydrochloride, 97% Pale brown solid Aripiprazole Impurity 35 Trazodone Impurity 1 Aripiprazole Impurity 36 Chlorophenyl Piperazine Hydrochloride Salt 1-(3-ChL Trazodone Chlorophenylpiperazine 1-(3-CHLOROPHENYL) PIPERAZINE HCL ( CPP HCl ) Aripiprazole Chlorophenyl piperazine Impurity 1-(m-Chlorphenyl)piperazinhydrochlorid Piperazine, 1-(3-chlorophenyl)-, hydrochloride (1:?) 1-(3-chlorophenyl)-Piperazine hydrochloride (1:) TRAZODONE CPP IMPURITY 1-(3-Ch Ioro Phenyl) Piperazine Hydrochloride 65369-76-8 13078-25-4 65369-76-7 C10H13ClN2xHCl C10H13ClN2HClC10H14Cl2N2 C10H13ClN2HCl 5-HT2c serotonin receptor agonist; metabolite of trazodone. Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Piperazines Serotonin receptor Piperazines API intermediates