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AC410

AC410 structure

CAS No.: 1361415-84-0

Chemical Name:: AC410

Synonyms: AC410;2-Quinazolinemethanol, α-(4-fluorophenyl)-4-[(5-methyl-1H-pyrazol-3-yl)amino]-, (αS)-

CBNumber:: CB33309910

Molecular Formula:: C19H16FN5O

Molecular Weight:: 349.3616432

MDL Number:

MOL File:: 1361415-84-0.mol

Last updated:2023-03-31 09:12:57

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AC410 Properties

Boiling point	528.8±50.0 °C(Predicted)
Density	1.421±0.06 g/cm3(Predicted)
pka	12.61±0.20(Predicted)

AC410 Chemical Properties,Uses,Production

Description

AC410 is a potent, selective, orally-administered, small molecule inhibitor of Janus kinase 2 (JAK2, Kd = 0.18 nM) and has potential utility in autoimmune and inflammatory indications. Activity data: the specificity of AC410 for JAK2 vis-a-vis JAK1 (Kd = 2.5 nM) and JAK3 (Kd = 5 nM).

AC410 Preparation Products And Raw materials

Raw materials

Preparation Products

AC410 Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	1701086315	dexuanpharma@126.com	China	9478	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28091	58

Supplier	Advantage
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	58
TargetMol Chemicals Inc.	58

AC410 2-Quinazolinemethanol, α-(4-fluorophenyl)-4-[(5-methyl-1H-pyrazol-3-yl)amino]-, (αS)- 1361415-84-0