ChemicalBook >> CAS DataBase List >>1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
- CAS No.
- 174689-39-5
- Chemical Name:
- 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
- Synonyms
- SR 59230A;SR59230AHCl;SR 59230A HYDROCHLORIDE;SR 59230A >=98% (HPLC), powder;(2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol;3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE;(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate;3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt;1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE;hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
- CBNumber:
- CB3331761
- Molecular Formula:
- C23H29NO6
- Molecular Weight:
- 415.49
- MDL Number:
- MFCD06795851
- MOL File:
- 174689-39-5.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Properties
storage temp. | Inert atmosphere,Room Temperature |
---|---|
solubility | DMSO: >10mg/mL |
form | powder |
color | white |
FDA UNII | Z4G2GB3YHU |
SAFETY
Risk and Safety Statements
Safety Statements | 22-24/25 |
---|---|
WGK Germany | 3 |
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S8688 | SR 59230A ≥98% (HPLC), powder | 174689-39-5 | 5mg | $165 | 2024-03-01 | Buy |
Sigma-Aldrich | S8688 | SR 59230A ≥98% (HPLC), powder | 174689-39-5 | 25mg | $228.4 | 2024-03-01 | Buy |
Tocris | 1511 | SR59230Ahydrochloride ≥98%(HPLC) | 174689-39-5 | 10 | $220 | 2021-12-16 | Buy |
Tocris | 1511 | SR59230Ahydrochloride ≥98%(HPLC) | 174689-39-5 | 50 | $926 | 2021-12-16 | Buy |
Usbiological | 256751 | SR 59230A hydrochloride | 174689-39-5 | 10mg | $466 | 2021-12-16 | Buy |
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4
Hazard
A poison.
Biological Activity
Potent and selective β 3 adrenoceptor antagonist (IC 50 values are 40, 408 and 648 nM for β 3 , β 1 and β 2 receptors respectively). Orally active in vivo . Also available as part of the β -Adrenoceptor Antagonist Tocriset™ .
Biochem/physiol Actions
SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Suppliers
Global( 55)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4287 | 55 | |
Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 27314 | 60 |
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Spectrum
174689-39-5(1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE)Related Search:
SR 59230A HYDROCHLORIDE
SR59230AHCl
3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt
SR 59230A
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate
SR 59230A >=98% (HPLC), powder
3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE
hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
(2S)-1-(2-ethylphenoxy)-3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino}propan-2-ol
174689-39-5
C21H27NO2HCl
Adrenoceptor