ChemicalBook >> CAS DataBase List >>Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- CAS No.
- 1278405-51-8
- Chemical Name:
- Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- Synonyms
- CHK-IN-1;CHKIN1,CHK IN 1;Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
- CBNumber:
- CB33339722
- Molecular Formula:
- C18H19ClFN5OS
- Molecular Weight:
- 407.8927632
- MDL Number:
- MFCD31382099
- MOL File:
- 1278405-51-8.mol
Last updated:2024-11-20 11:41:24
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Chemical Properties,Uses,Production
Description
CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].
References
[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1
Synthesis of Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride from (S)-tert-butyl 3-((7-carbamoyl-2-(3-fluorophenyl)thieno[2,3-d]pyridazin-4-yl)amino)piperidine-1-carboxylate
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24647 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
View Lastest Price from Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride manufacturers
Thieno[2,3-d]pyridazine-7-carboxamide, 2-(3-fluorophenyl)-4-[(3S)-3-piperidinylamino]-, hydrochloride
CHK-IN-1
CHKIN1,CHK IN 1
1278405-51-8