Triphenylmethanol
- CAS No.
- 76-84-6
- Chemical Name:
- Triphenylmethanol
- Synonyms
- TRT-OH;TRIPHENYLCARBINOL;TRITYL ALCOHOL;Tritanol;Triphenylmethanol, (Triphenyl carbinol;Ih-Tetrazole;tirphenylmethanol;Triphenylmethanol ,99%;Triphenylmethyl alcohol;Triphenylmethanol(76-84-6)
- CBNumber:
- CB3335936
- Molecular Formula:
- C19H16O
- Molecular Weight:
- 260.33
- MDL Number:
- MFCD00004445
- MOL File:
- 76-84-6.mol
- MSDS File:
- SDS
| Melting point | 160-163 °C (lit.) |
|---|---|
| Boiling point | 360 °C (lit.) |
| Density | d40 1.199 |
| refractive index | 1.6220 (estimate) |
| Flash point | 360-380°C |
| storage temp. | 2-8°C |
| solubility | dioxane: 0.1 g/mL, clear |
| pka | 12.73±0.29(Predicted) |
| form | Fine Crystalline Powder |
| color | White to light yellow |
| Appearance | White to Light yellow to Light orange powder to crystal |
| Water Solubility | INSOLUBLE |
| Merck | 14,9739 |
| BRN | 1460837 |
| Stability | Stable. Combustible. Incompatible with oxidizing agents, acids, acid chlorides, acid anhydrides. |
| CAS DataBase Reference | 76-84-6(CAS DataBase Reference) |
| FDA UNII | U97Q0OU9KB |
| NIST Chemistry Reference | Benzenemethanol, «alpha»,«alpha»-diphenyl-(76-84-6) |
| EPA Substance Registry System | Benzenemethanol, .alpha.,.alpha.-diphenyl- (76-84-6) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 38-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29062900 | |||||||||
| NFPA 704 |
|
Triphenylmethanol price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.21196 | Triphenylmethanol for synthesis | 76-84-6 | 50g | $75.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.21196 | Triphenylmethanol for synthesis | 76-84-6 | 250g | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | 134848 | Triphenylmethanol 97% | 76-84-6 | 50g | $68.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 134848 | Triphenylmethanol 97% | 76-84-6 | 250g | $252 | 2024-03-01 | Buy |
| TCI Chemical | T0516 | Triphenylmethanol >99.0%(GC) | 76-84-6 | 25g | $38 | 2024-03-01 | Buy |
Triphenylmethanol Chemical Properties,Uses,Production
Chemical Properties
Triphenylmethanol is a white powder or colorless, isolated crystals that are soluble in alcohol, ether, and benzene. It turns dark yellow when dissolved in concentrated sulfuric acid, colorless when dissolved in glacial acetic acid, and is insoluble in water and petroleum ether. It distills at 360-380°C without decomposition.
Uses
Triphenylmethanol (Zidovudine EP Impurity D) is a triaryl methane derivative as antiproliferative agent.
Uses
Triphenylmethanol is used as a reagent in the research laboratory. It acts as an intermediate in the production of the commercially useful triarylmethane dyes. It is used in the preparation of triphenylmethane. It is also used as an antiproliferative agent. Further, it is used in the preparation of two-electron reduction product of pyrylogen. In addition to this, it reacts with triphenylphosphine oxide to form a 1:1 molecular complex. It serves as a specific clathrate host for methanol and dimethyl sulphoxide and forms clathrate inclusion complexes.
Triphenylmethanol was used in the synthesis of of the two-electron reduction product of pyrylogen.
It undergoes reduction to triphenylmethane by 9, 10-dihydro-10-methylacridine in the presence of perchloric acid.
Preparation
Triphenylmethanol synthesis: Triphenylmethanol was prepared by the action of benzene with carbon tetrachloride in the presence of Aluminum chloride, followed by acidification and hydrolysis.
Triphenylmethanol can also be prepared by the reaction of phenylmagnesium bromide with methyl benzoate (instead of benzophenone).
Synthesis of Triphenylmethanol
Reactions
The first one is the formation of the triphenylmethyl bromide from the reaction of triphenylmethanol with hydrobromic acid.
The second reaction is the formation of an ether from the reaction of triphenylmethanol with methanol in acidic conditions.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 839, 1955
The Journal of Organic Chemistry, 57, p. 4555, 1992 DOI: 10.1021/jo00042a044
General Description
Triphenylmethanol forms 1:1 molecular complex with triphenylphosphine oxide. It is a specific clathrate host for methanol and dimethyl sulphoxide and forms clathrate inclusion complexes. It undergoes reduction to triphenylmethane by 9, l0-dihydro-10-methylacridine in the presence of perchloric acid.
Materials Uses
Triphenylmethanol (TPOH) is a non-fluorescent compound that emits strong fluorescence in an aggregate state or on a solid surface after irradiation by UV light at 254 nm (UV1). Interestingly, the photo-induced fluorescence of TPOH was quenched when irradiated by UV light at a longer wavelength of 365 nm (UV2) and further repeatable on and off by UV1 and UV2, respectively. The reversible activation and deactivation of fluorescence at a solid surface could be repeatable at least 5 times. TPOH is thus applied for rewritable photopatterning tuned by UV light[1].
Purification Methods
Crystallise the carbinol from EtOH, MeOH, CCl4 (4mL/g), *benzene, hexane or pet ether (b 60-70o). Dry it at 90o. [Ohwada et al. J Am Chem Soc 108 3029 1986, Beilstein 6 IV 5014.]
References
[1] Zheng, Yue et al. “Photoactivatable aggregation-induced emission of triphenylmethanol?.” Chemical Communications 81 (2017): 11130–11133.
Triphenylmethanol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 3514 | 55 |
Related articles
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- Sep 14，2024
Related Qustion
- Q:What is the sturcture of Triphenylmethanol
- A:Triphenylmethanol features three phenyl (Ph) rings and an alcohol group bound to a central tetrahedral carbon atom.
- Nov 2，2024
View Lastest Price from Triphenylmethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-24 | Triphenylmethanol
76-84-6
|
US $5.00 / kg | 1kg | ≥98.5% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2025-04-23 | Triphenylmethanol
76-84-6
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-15 | Triphenylmethanol
76-84-6
|
US $70.00-25.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- Triphenylmethanol
76-84-6
- US $5.00 / kg
- ≥98.5%
- Jinan Finer Chemical Co., Ltd
-
- Triphenylmethanol
76-84-6
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Triphenylmethanol
76-84-6
- US $70.00-25.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd