4-Nonylphenylboronic acid
- CAS No.
- 256383-45-6
- Chemical Name:
- 4-Nonylphenylboronic acid
- Synonyms
- AKOS BRN-0129;FAAH/MAGL-IN-4;Nonylbenzeneboronic acid;(4-nonylphenyl)boronicaci;4-Nonylphenylboronic acid;4-N-nonylphenylbronic acid;4-N-NONYLPHENYLBORONIC ACID;1-Borono-4-(non-1-yl)benzene;4-N-NONYLBENZENEBORONIC ACID;4-(Non-1-yl)benzeneboronic acid
- CBNumber:
- CB3346668
- Molecular Formula:
- C15H25BO2
- Molecular Weight:
- 248.17
- MDL Number:
- MFCD02093070
- MOL File:
- 256383-45-6.mol
- MSDS File:
- SDS
| Melting point | 82-85°C |
|---|---|
| Boiling point | 385.3±35.0 °C(Predicted) |
| Density | 0.97±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 30 mg/ml) |
| form | solid |
| pka | 8.72±0.16(Predicted) |
| color | White |
| Water Solubility | Insoluble in water. |
| BRN | 8215118 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| CAS DataBase Reference | 256383-45-6(CAS DataBase Reference) |
| FDA UNII | 2SY8DS7Y3D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
4-Nonylphenylboronic acid price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | L17753 | 4-n-Nonylbenzeneboronic acid, 98+% | 256383-45-6 | 1g | $95.65 | 2024-03-01 | Buy |
| Alfa Aesar | L17753 | 4-n-Nonylbenzeneboronic acid, 98+% | 256383-45-6 | 5g | $412 | 2024-03-01 | Buy |
| Cayman Chemical | 13140 | 4-(n-nonyl) Benzeneboronic Acid ≥98% | 256383-45-6 | 100mg | $19 | 2024-03-01 | Buy |
| Cayman Chemical | 13140 | 4-(n-nonyl) Benzeneboronic Acid ≥98% | 256383-45-6 | 1g | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 13140 | 4-(n-nonyl) Benzeneboronic Acid ≥98% | 256383-45-6 | 250mg | $39 | 2024-03-01 | Buy |
4-Nonylphenylboronic acid Chemical Properties,Uses,Production
Description
Nonylbenzeneboronic acid (CAS 256383-45-6) is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH, the enzyme which hydrolyzes and deactivates anandamide), IC50=9.1 nM1. Also inhibits monoacylglycerol lipase (MAGL, the enzyme which hydrolyzes 2-arachidonoyl-glycerol), IC50=7.9 μM.1
Uses
4-n-Nonylbenzeneboronic acid is a potent inhibitor of fatty acid amide hydrolase. It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG).
in vitro
4-(n-nonyl) benzeneboronic acid was synthezed as a potent inhibitor of faah, with an ic50 of 9.1 nm. 4-(n-nonyl) benzeneboronic acid was also found to be able to inhibit magl, which could hydrolyze 2-arachidonoyl glycerol, but at around 1000-fold higher concentration. moreover, it was found that as the most potent para-substituted compound, 4-(n-nonyl) benzeneboronic acid showed rather high pka of 9.1. in addition, the molecular docking was utilized to gain insight on the faah binding mode of 4-(n-nonyl) benzeneboronic acid and a putative binding mode was observed [1].
IC 50
9.1 nm
References
1) Minkkila?et al.?(2008),?Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase; J. Med. Chem.,?51?7057
4-Nonylphenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Nonylphenylboronic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49979 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
View Lastest Price from 4-Nonylphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | 4-Nonylphenylboronic acid
256383-45-6
|
US $32.00 / mg | 99.13% | 10g | TargetMol Chemicals Inc. |
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- 4-Nonylphenylboronic acid
256383-45-6
- US $32.00 / mg
- 99.13%
- TargetMol Chemicals Inc.