ChemicalBook >> CAS DataBase List >>7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide structure

CAS No.: 1328934-40-2

Chemical Name:: 7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

Synonyms: [2H6]-LEE011;2H6]-Ribociclib;7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide

CBNumber:: CB33598099

Molecular Formula:: C23H24D6N8O

Molecular Weight:: 440.574270668

MDL Number:

MOL File:: 1328934-40-2.mol

Last updated:2024-07-02 08:55:06

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7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide Properties

form	Solid
color	Light yellow to yellow

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	L321002	LEE011-d6	1328934-40-2	25mg	$1320	2021-12-16	Buy
ChemScene	CS-0131861	RibociclibD6 99.47%	1328934-40-2	5mg	$580	2021-12-16	Buy
ChemScene	CS-0131861	RibociclibD6 99.47%	1328934-40-2	10mg	$980	2021-12-16	Buy

Product number	Packaging	Price	Buy
L321002	25mg	$1320	Buy
CS-0131861	5mg	$580	Buy
CS-0131861	10mg	$980	Buy

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide Chemical Properties,Uses,Production

Uses

LEE011-d6 is the isotope analog of LEE011(L321000). LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models.

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide Suppliers

Global( 13)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Novel Biomedical Co., Ltd.	028-85255396 18302801538	cdnovell@163.com	China	2292	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	info@synzest.com	China	9287	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Shanghai Jidu Biotechnology Co., Ltd.	13851761812	13851761812@163.com	China	498	58
Shanghai Beiwanta Biotechnology Co., Ltd.	021-67187366 19901745723	info@bwtlab.com	China	9255	58
Nanjing Shizhou Biology Technology Co.,Ltd	17301488900	judy.xia@synzest.com	China	12582	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	rose.shi@synzest.com	China	6210	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9268	58
SHANGHAI ZZBIO CO., LTD.	13916577892 19921389125	tech@zzbioco.com	China	12063	58

Supplier	Advantage
Chengdu Novel Biomedical Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Energy Chemical	58
Shanghai Jidu Biotechnology Co., Ltd.	58
Shanghai Beiwanta Biotechnology Co., Ltd.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
RD International Technology Co., Limited	58
SHANGHAI ZZBIO CO., LTD.	58

7-cyclopentyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide [2H6]-LEE011 2H6]-Ribociclib 1328934-40-2