Muscarinic toxin 1
- CAS No.
- Chemical Name:
- Muscarinic toxin 1
- Synonyms
- MT1;MTX1;MEL-1A-R;MT1; MT 1;MUSCARINIC TOXIN 1;Mel1a melatonin receptor;Anti-MTR1A antibody produced in rabbit;Anti-MTNR1A antibody produced in rabbit;Muscarinic Toxin-1 from Dendroaspis angusticeps venom;LEU-THR-CYS-VAL-THR-SER-LYS-SER-ILE-PHE-GLY-ILE-THR-THR-GLU-ASN-CYS-PRO-ASP-GLY-GLN-ASN-LEU-CYS-PHE-LYS-LYS-TRP-TYR-TYR-ILE-VAL-PRO-ARG-TYR-SER-ASP-ILE-THR-TRP-GLY-CYS-ALA-ALA-THR-CYS-PRO-LYS-PRO-THR-ASN-VAL-ARG-GLU-THR-ILE-ARG-CYS-CYS-GLU-THR-ASP-LYS-CYS-ASN-GLU
- CBNumber:
- CB3392337
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00286052
- MOL File:
- Mol file
Muscarinic toxin 1 price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4501929 | Anti-MTR1A antibody produced in rabbit affinity isolated antibody | 100μG | $485 | 2023-01-07 | Buy | |
| Biorbyt Ltd | orb599212 | MTX1 | 10μg | $290.7 | 2021-12-16 | Buy | |
| DC Chemicals | DC10023 | MT-1 >98% | 100mg | $1200 | 2021-12-16 | Buy | |
| DC Chemicals | DC10023 | MT-1 >98% | 250mg | $2000 | 2021-12-16 | Buy |
Muscarinic toxin 1 Chemical Properties,Uses,Production
Origin
Muscarinic toxin 1 was originally isolated from mamba venom and consists of 65 to 66 amino acid residues with four intramolecular disulfide bonds. Recent studies have shown that activation of muscarinic acetylcholine receptors regulates the metabolism of β-amyloid precursor proteins, and that muscarinic agonists reduce the production of amyloid-β proteins.
Biological Functions
Muscarinic toxin 1 has non-competitive interactions with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC50=2.3 nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B) and alpha-2c (ADRA2C) adrenergic receptors. Reversibly binds to the M1 (CHRM1) muscarinic acetylcholine receptor, probably through interaction with the orthosteric site. Also has slightly weaker effects on M3 (CHRM3) and M4 (CHRM4) receptors. The order of potency is ADRA2B>>CHRM1>ADRA1A>ADRA1B>ADRA2C/CHRM4 (PubMed:24793485).
Muscarinic toxin 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Muscarinic toxin 1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao Xinli Technology Development Co., Ltd. | +8616632313095 | xinlikeji01@qdxlchem.com | China | 60 | 58 |
| Zhengzhou Hanke Import and export Trade Co. LTD | +8613838064731 | sales1@zzybchem.com | China | 66 | 58 |
| Hubei Lange Biotechnology Co., Ltd. | +8617762501948 | sales2@langebiotech.com | China | 154 | 58 |
| Shenzhen Sendi Biotechnology Co.Ltd. | 0755-23311925 18102838259 | Abel@chembj.com | CHINA | 3191 | 55 |
| Shenzhen Simeiquan Biotechnology Co. Ltd | 18126413629 0755-23311925 2355327053 | abel@ycgmp.com | China | 5115 | 58 |
| Hefei KS-V Peptide Biotechnology Co., Ltd. | 0551-65120828 17368858770 | sales1@difficultpeptide.com | China | 118 | 58 |
