HEPARIN MONOSULFATE SODIUM SALT
- CAS No.
- 57459-72-0
- Chemical Name:
- HEPARIN MONOSULFATE SODIUM SALT
- Synonyms
- Leparan;suleparoid;Aids031652;Aids-031652;HeparanSulphate;HEPARITIN SULFATE;suleparoid sodium;heparin monosulfate;Sodium heparan sulfate;Sodium heparitin sulfate
- CBNumber:
- CB3430192
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131294
- MOL File:
- Mol file
storage temp. | 2-8°C |
---|---|
solubility | H2O: 1 mg/mL, clear, colorless |
EWG's Food Scores | 1 |
FDA UNII | X19199D45C |
SAFETY
Risk and Safety Statements
WGK Germany | 3 |
---|---|
F | 10 |
HEPARIN MONOSULFATE SODIUM SALT price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H7640 | Heparan sulfate sodium salt from bovine kidney | 57459-72-0 | 1mg | $200 | 2024-03-01 | Buy |
Sigma-Aldrich | H7640 | Heparan sulfate sodium salt from bovine kidney | 57459-72-0 | 5mg | $701 | 2024-03-01 | Buy |
Sigma-Aldrich | H7640 | Heparan sulfate sodium salt from bovine kidney | 57459-72-0 | 10mg | $1230 | 2024-03-01 | Buy |
Usbiological | 297228 | Heparan sulfate sodium salt | 57459-72-0 | 2mg | $814 | 2021-12-16 | Buy |
Usbiological | H1890-55 | Heparan Sulfate, Sodium Salt, Bovine | 57459-72-0 | 1mg | $442 | 2021-12-16 | Buy |
HEPARIN MONOSULFATE SODIUM SALT Chemical Properties,Uses,Production
Chemical Properties
Also available fractionated heparan sulfates with lower molecular weights and different Anti-IIa activities.
Uses
Heparan sulfate sodium salt from bovine kidney has been used:
- to investigate its effect on proliferation of B cells
- to monitor its role on eye development in E5 embryonic cells
- to study its binding with exosome fibronectin in human trabecular meshwork cells using dot blot
Uses
Antithrombotic.
brand name
Orgaran (Organon).
Biochem/physiol Actions
Heparan sulphate (HS), a ubiquitous glycosaminoglycan, is a polymer of D-glucuronic acid or L-iduronic acid and D-glucosamine (GlcA) sugars. It is synthesized in the cis-Golgi as heparan. In Golgi, final heparan sulphate is synthesized in by the action of enzymes N- and O-HS-sulphotransferases and HS epimerase. The mature HS has 50 to 200 disaccharide units. It is part of the extracellular matrix (ECM) and plays a key role in the oncogenic pathway. Deregulation of heparin sulfate metabolism is implicated in cancer progression. HS is associated with the onset of infectious diseases and inflammatory conditions. HS interaction with Aβ fibrils contributes to the pathophysiology of Alzheimer′s disease.
HEPARIN MONOSULFATE SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
HEPARIN MONOSULFATE SODIUM SALT Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6005 | 58 |
Supplier | Advantage |
---|---|
Henan Tianfu Chemical Co.,Ltd. | 55 |
BOC Sciences | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
Sigma-Aldrich | 80 |
Carbosynth | 58 |