ChemicalBook >> CAS DataBase List >>4,4'-Dimethoxytrityl chloride
4,4'-Dimethoxytrityl chloride
- CAS No.
- 40615-36-9
- Chemical Name:
- 4,4'-Dimethoxytrityl chloride
- Synonyms
- DMT;DMT-CL;4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene);4,4-DIMETHOXYTRITYL CHLORIDE;Dimethoxy Trityl Chloride;EPB49;DMT-Cl)D;DMTRT-CL;NSC 89782;DMT CHLORIDE
- CBNumber:
- CB3442487
- Molecular Formula:
- C21H19ClO2
- Molecular Weight:
- 338.83
- MDL Number:
- MFCD00008409
- MOL File:
- 40615-36-9.mol
Last updated:2025-01-08 13:38:03
| Melting point | 123-125 °C |
|---|---|
| Boiling point | 455.07°C (rough estimate) |
| Density | 1.0887 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.5330 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| color | Pink |
| Water Solubility | Soluble in chloroform and methanol. Partially soluble in water |
| Sensitive | Moisture Sensitive |
| BRN | 2471942 |
| Stability | Hygroscopic, Moisture Sensitive |
| InChIKey | JBWYRBLDOOOJEU-UHFFFAOYSA-N |
| LogP | 5.74 at 20℃ |
| CAS DataBase Reference | 40615-36-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Methane, chlorobis(p-methoxyphenyl)phenyl-(40615-36-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H317-H335-H411 | |||||||||
| Precautionary statements | P260-P271-P273-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-34 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36-45-36/37/39 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29093090 | |||||||||
| Toxicity | A hallucinogenic (psychedelic) agent that may catalyze the onset of emotional problems or psychosis in predisposed individuals. DMT is perhaps one of the least studied of the hallucinogens. It causes perceptual alterations and illusions, including changes in touch, taste, and odor. The thinking process is substantially altered; there are hallucinations and loss of contact with reality. There have been no overdose deaths attributed to the direct effects of DMT. The drug is very short-acting, with a duration of effect of about half an hour or less. | |||||||||
| NFPA 704 |
|
4,4'-Dimethoxytrityl chloride price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 100013 | 4,4′-Dimethoxytrityl chloride 95% | 40615-36-9 | 5g | $61.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 100013 | 4,4′-Dimethoxytrityl chloride 95% | 40615-36-9 | 25g | $173 | 2024-03-01 | Buy |
| TCI Chemical | D1612 | 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent] >97.0%(HPLC)(T) | 40615-36-9 | 5g | $42 | 2024-03-01 | Buy |
| TCI Chemical | D1612 | 4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent] >97.0%(HPLC)(T) | 40615-36-9 | 25g | $122 | 2024-03-01 | Buy |
| Alfa Aesar | A11626 | 4,4'-Dimethoxytrityl chloride, 98% | 40615-36-9 | 5g | $46.65 | 2024-03-01 | Buy |
4,4'-Dimethoxytrityl chloride Chemical Properties,Uses,Production
Chemical Properties
4,4'-Dimethoxytrityl chloride is pink powder
Uses
4,4'-Dimethoxytrityl chloride is a versatile protecting group for primary alcohols, specially useful in oligonucleotide synthesis
Uses
4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.
Uses
Hydroxyl protecting group for nucleosides and nucleotides.
Flammability and Explosibility
Not classified
Purification Methods
DMT crystallises from cyclohexane/acetyl chloride as the hydrochloride. Dry it over KOH pellets in a desiccator. When dissolved in *C6H6 and air is blown through, HCl is removed. It crystallises from Et2O. [Baeyer & Villiger Chem Ber 36 2788 1903, Smith et al. J Am Chem Soc 84 430 1962, Smith et al. J Am Chem Soc 85 3821 1963.] Ifit has hydrolysed considerably (see OH in IR), then repeat the crystallisation from cyclohexane/acetyl chloride — excess of AcCl is removed in a vacuum over KOH, then recrystallise it from Et2O. [Beilstein 6 IV 1042.]
4,4'-Dimethoxytrityl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
5''-O-(4,4''-Dimethoxytrityl)-inosine
5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
DMT-DCYTIDINE (N6-BENZOYL) CYANOETHYL PHOSPHORAMIDITE)
5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE
5'-O-(4,4'-DIMETHOXYTRITYL)-N4-ACETYL-2'-DEOXYCYTIDINE
DMT-dG(dmf) Phosphoramidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
Acetamide, N-[3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-2,2,2-trifluoro-
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI)
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Global( 634)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12832 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7712 | 58 |
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| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18148 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20274 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 3001 | 58 |
| INNOBIO PHARM CO.,LTD | +8615600141006 | cindyyb@126.com | China | 269 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18750 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
View Lastest Price from 4,4'-Dimethoxytrityl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-09 | 4,4'-Dimethoxytrityl chloride
40615-36-9
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2025-01-09 | 4,4’-Dimethoxytriryl Chloride
40615-36-9
|
US $0.00-0.00 / kg | 1kg | 98% | 20tons | INNOBIO PHARM CO.,LTD | |
 |
2025-01-06 | 4,4'-Dimethoxytrityl chloride
40615-36-9
|
US $0.00-0.00 / kg | 1kg | 98 | 500 | Wuhan Circle Star Chem-medical Technology Co.,Ltd |
-
- 4,4'-Dimethoxytrityl chloride
40615-36-9
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 4,4’-Dimethoxytriryl Chloride
40615-36-9
- US $0.00-0.00 / kg
- 98%
- INNOBIO PHARM CO.,LTD
-
- 4,4'-Dimethoxytrityl chloride
40615-36-9
- US $0.00-0.00 / kg
- 98
- Wuhan Circle Star Chem-medical Technology Co.,Ltd
40615-36-9(4,4'-Dimethoxytrityl chloride)Related Search:
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4,4-DIMETHOXYTRITYL CHLORIDE
Dimethoxy Trityl Chloride
4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene)
DMT-CL
DMT
-Dimethoxytrityl chloride
99% 44’Dimethoxytriphenylmethyl chlide 40615-36-9 CAS NO.40615-36-9
4,4'-Dimethoxytrityl chloride