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2,3,5,6-Tetrafluoropyridine

2,3,5,6-Tetrafluoropyridine structure

CAS No.: 2875-18-5

Chemical Name:: 2,3,5,6-Tetrafluoropyridine

Synonyms: 2,3,5,6-TetrafL;2,3,5,6-TETRAFLUOROPYRIDINE;Pyridine,2,3,5,6-tetrafluoro-;2,3,5,6-Tetrafluoropyridine98%;2,3,5,6-Tetrafluoropyridine,99%;2,3,5,6-Tetrafluoropyridine 98%;N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)- &;2,3,5,6-Tetrafluoropyridine ISO 9001：2015 REACH

CBNumber:: CB3444784

Molecular Formula:: C5HF4N

Molecular Weight:: 151.06

MDL Number:: MFCD00011734

MOL File:: 2875-18-5.mol

MSDS File:: SDS

Last updated:2024-10-24 21:11:35

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2,3,5,6-Tetrafluoropyridine Properties

Boiling point	102 °C (lit.)
Density	1.499 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4046(lit.)
Flash point	87 °F
storage temp.	Inert atmosphere,2-8°C
pka	-10.94±0.20(Predicted)
form	clear liquid
color	Colorless to Light yellow
Specific Gravity	1.52
InChI	InChI=1S/C5HF4N/c6-2-1-3(7)5(9)10-4(2)8/h1H
InChIKey	HWIPMBCMGVXOKN-UHFFFAOYSA-N
SMILES	C1(F)=NC(F)=C(F)C=C1F
CAS DataBase Reference	2875-18-5(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2,3,5,6-tetrafluoro-(2875-18-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H226-H315-H319-H335

Precautionary statements

P210-P302+P352-P305+P351+P338

Hazard Codes

Xi,F,C

Risk Statements

10-36/37/38

Safety Statements

28-36

RIDADR

UN 1993 3/PG 3

WGK Germany

Hazard Note

Flammable/Irritant

HazardClass

PackingGroup

III

HS Code

29333990

NFPA 704

	2
2		0

2,3,5,6-Tetrafluoropyridine price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	316679	2,3,5,6-Tetrafluoropyridine 95%	2875-18-5	1g	$65.2	2023-06-20	Buy
TCI Chemical	T1778	2,3,5,6-Tetrafluoropyridine >98.0%(GC)	2875-18-5	1g	$48	2024-03-01	Buy
TCI Chemical	T1778	2,3,5,6-Tetrafluoropyridine >98.0%(GC)	2875-18-5	5g	$144	2024-03-01	Buy
Alfa Aesar	B21905	2,3,5,6-Tetrafluoropyridine, 97%	2875-18-5	1g	$41.1	2021-12-16	Buy
Alfa Aesar	B21905	2,3,5,6-Tetrafluoropyridine, 97%	2875-18-5	5g	$140	2021-12-16	Buy

Product number	Packaging	Price	Buy
316679	1g	$65.2	Buy
T1778	1g	$48	Buy
T1778	5g	$144	Buy
B21905	1g	$41.1	Buy
B21905	5g	$140	Buy

2,3,5,6-Tetrafluoropyridine Chemical Properties,Uses,Production

Synthesis

Catalytic reduction of aryl chlorides, bromides and iodides is well documented, however, aryl fluorides do not readily react under these conditions, owing to the strong C-F bond and the high activation barrier to bond breaking. Work in our laboratories showed that at high temperatures, pentafluoropyridine was converted to 2,3,5,6- tetrafluoropyridine using a palladium catalyst.
2,3,5,6-Tetrafluoropyridine

Preparation

An autoclave sprayed with PTFE was charged with pentafluoropyridine (20.0 g, 118 mmol), HBr (32.0 g, 400 mmol) and sulpholane (40 cm³) and heated at 200 ℃ for 48 h. The mixture was added to water and extracted into ether. The ether solution was shown to contain pentafluoropyridine (79%) and 2,3,5,6-tetrafluoropyridine (21%) by comparison of their GCMS and fluorine nmr spectra with authentic samples.

Description

Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medicine, pesticides, rubber, dyes and other fields. Since the 1960s, there have been hundreds of medicines, pesticides, dyes, and some special reagents developed with fluorine-containing aromatic compounds as intermediates. In the weakly basic pyridine ring, the nitrogen atom is more negatively charged, and then a fluorine atom with a strong electronegativity is introduced to synthesize a fluorine-containing pyridine intermediate.

Chemical Properties

clear colorless liquid

2,3,5,6-Tetrafluoropyridine synthesis

Synthesis of 2,3,5,6-Tetrafluoropyridine from 2,3,5,6-Tetrachloropyridine

2,3,5,6-Tetrafluoropyridine Preparation Products And Raw materials

Raw materials

Pyridine, 2,3,5,6-tetrafluoro-4-(trimethylsilyl)- 4,4'-Bipyridine, 2,2',3,3',5,5',6,6'-octafluoro- FLUOROTRIETHYLSILANE 4-Bromo-2,3,5,6-tetrafluoropyridine Triphenylsilane

Methyl 4-bromobenzoate Pentafluoropyridine

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Preparation Products

2,5-Difluoropyridine 2,3,4,6-TETRAFLUOROPYRIDINE 3,4,5-Trifluoropyridine 2,3,6-TRIFLUOROPYRIDINE 2,3,4,5-Tetrafluoropyridine

2,3,5,6-Tetrafluoropyridine Suppliers

Global( 301)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Guangzhou CATO Research Chemicals Inc.	+86-020-81960175-617 +8615602392859	Intermediate@cato-chem.com	China	8047	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20283	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Dongfan Chem. Co., Ltd.	021-34500607 13391355195	sales@dfanchem.com	CHINA	61	55
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1376	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Klong Industrial Co., Ltd	0086-519-68231162	info@klongchem.com	CHINA	131	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10311	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58

Supplier	Advantage
Guangzhou CATO Research Chemicals Inc.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Dongfan Chem. Co., Ltd.	55
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Klong Industrial Co., Ltd	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58

Synthesis and Application of Tetrafluoropyridine
Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medici....
Dec 9，2019

View Lastest Price from 2,3,5,6-Tetrafluoropyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-17	2,3,5,6-Tetrafluoropyridine 2875-18-5	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
2024-04-02	2,3,5,6-Tetrafluoropyridine 2875-18-5	US $5.00-0.20 / KG	1KG	98%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-03-15	2,3,5,6-Tetrafluoropyridine 2875-18-5	US $0.00-0.00 / kg	1kg	98%Min	1000kg	LY Global chemicals co.,ltd .

2,3,5,6-Tetrafluoropyridine
2875-18-5
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

2,3,5,6-Tetrafluoropyridine
2875-18-5
US $5.00-0.20 / KG
98%
Henan Fengda Chemical Co., Ltd

2,3,5,6-Tetrafluoropyridine
2875-18-5
US $0.00-0.00 / kg
98%Min
LY Global chemicals co.,ltd .

2,3,5,6-Tetrafluoropyridine Spectrum

2,3,5,6-Tetrafluoropyridine(2875-18-5)MS 2,3,5,6-Tetrafluoropyridine(2875-18-5)¹HNMR 2,3,5,6-Tetrafluoropyridine(2875-18-5)¹³CNMR 2,3,5,6-Tetrafluoropyridine(2875-18-5)IR1 2,3,5,6-Tetrafluoropyridine(2875-18-5)Raman

2875-18-5(2,3,5,6-Tetrafluoropyridine)Related Search:

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2,3,5,6-TETRAFLUOROPYRIDINE 2,3,5,6-Tetrafluoropyridine 98% 2,3,5,6-Tetrafluoropyridine98% 2,3,5,6-Tetrafluoropyridine,99% N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)- & Pyridine,2,3,5,6-tetrafluoro- 2,3,5,6-TetrafL 2,3,5,6-Tetrafluoropyridine ISO 9001：2015 REACH 2875-18-5 2875-18-8 C5HF4N Fluoropyridines C5 Building Blocks Pyridines Heterocyclic Building Blocks Halopyridines Fluorine series Pyridine Heterocyclic Compounds Fluoropyridines Halopyridines C5 Heterocyclic Building Blocks Pyridines