1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CAS No.
- 474944-25-7
- Chemical Name:
- 1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Synonyms
- C16-04:1 PC;BUTENOYL PAF;1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1-O-HEXADECYL-2-O-(2E-BUTENOYL)-SN-GLYCERYL-3-PHOSPHOCHOLINE
- CBNumber:
- CB3456857
- Molecular Formula:
- C28H56NO7P
- Molecular Weight:
- 549.72
- MDL Number:
- MFCD02259314
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 60929 | Butenoyl PAF ≥98% | 474944-25-7 | 1mg | $79 | 2024-03-01 | Buy |
| Cayman Chemical | 60929 | Butenoyl PAF ≥98% | 474944-25-7 | 5mg | $351 | 2024-03-01 | Buy |
| Cayman Chemical | 60929 | Butenoyl PAF ≥98% | 474944-25-7 | 10mg | $623 | 2024-03-01 | Buy |
| Cayman Chemical | 60929 | Butenoyl PAF ≥98% | 474944-25-7 | 50mg | $2716 | 2024-03-01 | Buy |
| ApexBio Technology | C5385 | ButenoylPAF | 474944-25-7 | 5mg(solution) | $400 | 2021-12-16 | Buy |
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Uses,Production
Definition
ChEBI: PC(O-16:0/4:1) is a phosphatidylcholine O-20:1.
Biological Activity
butenoyl paf is a paf receptor agonist [1].platelet activating factor (paf), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages. paf play important roles in a variety of pathophysiological states including acute allergy, inflammation, asthma, gastrointestinal ulceration, and toxic shock [1][2].butanoyl-paf and butenoyl paf are both products of the oxidative decomposition of 2-arachidonoyl phospholipids. although butenoyl paf is 10-fold less potent than paf as a paf receptor agonist and ligand, it is 100-fold more abundant in oxidized ldl than paf. therefore, oxidation products of ldl phospholipids were physiologically relevant bioactive paf-like molecules [1].
References
[1]. marathe gk, davies ss, harrison ka, et al. inflammatory platelet-activating factor-like phospholipids in oxidized low density lipoproteins are fragmented alkyl phosphatidylcholines. j biol chem. 1999 oct 1;274(40):28395-404.
[2]. davies ss, pontsler av, marathe gk, et al. oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. j biol chem. 2001 may 11;276(19):16015-23.
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
1-O-HEXADECYL-2-BUTENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| ApexBio Technology | 58 |