Deoxycorticosterone acetate
- CAS No.
- 56-47-3
- Chemical Name:
- Deoxycorticosterone acetate
- Synonyms
- doxo;DOCA;steraq;arcort;ocriten;syncort;cortate;percotol;syncorta;unidocan
- CBNumber:
- CB3462948
- Molecular Formula:
- C23H32O4
- Molecular Weight:
- 372.5
- MDL Number:
- MFCD00003660
- MOL File:
- 56-47-3.mol
Melting point | 157°C |
---|---|
alpha | D20 +168 to +176° (dioxane) |
Boiling point | 421.94°C (rough estimate) |
Density | 1.0415 (rough estimate) |
refractive index | 175 ° (C=1, Dioxane) |
storage temp. | Sealed in dry,Room Temperature |
solubility | H2O: insoluble |
form | Solid |
color | White to Off-White |
Water Solubility | 4mg/L(25 ºC) |
Merck | 2901 |
BRN | 2570798 |
InChI | InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 |
InChIKey | VPGRYOFKCNULNK-ACXQXYJUSA-N |
SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2 |
LogP | 3.080 |
CAS DataBase Reference | 56-47-3(CAS DataBase Reference) |
FDA UNII | 6E0A168OB8 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H373-H360 |
Precautionary statements | P260-P314-P501 |
Safety Statements | 22-24/25 |
RIDADR | UN 2811 |
WGK Germany | 3 |
RTECS | HG0525000 |
HazardClass | IRRITANT |
HS Code | 2937290000 |
Deoxycorticosterone acetate price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 1g | $207 | 2024-03-01 | Buy |
Sigma-Aldrich | 1174001 | Deoxycorticosterone acetate United States Pharmacopeia (USP) Reference Standard | 56-47-3 | 200mg | $174.4 | 2024-03-01 | Buy |
Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 5g | $673 | 2024-03-01 | Buy |
Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 25g | $1590 | 2024-03-01 | Buy |
Sigma-Aldrich | D0400000 | Desoxycortone acetate European Pharmacopoeia (EP) Reference Standard | 56-47-3 | d0400000 | $220 | 2024-03-01 | Buy |
Deoxycorticosterone acetate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Adrenocortical/mineralocorticoid Steroid.
Uses
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Definition
ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.
brand name
Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].
General Description
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
Purification Methods
11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Deoxycorticosterone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan Han Sheng New Material Technology Co.,Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2097 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5975 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from Deoxycorticosterone acetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-13 | Deoxycorticosterone acetate
56-47-3
|
US $0.00-0.00 / kg | 1kg | 99.1 | 100KG | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | Deoxycorticosterone acetate
56-47-3
|
US $46.00-36.00 / mg | 99.81% | 10g | TargetMol Chemicals Inc. | |||
2024-03-08 | corticosterone
56-47-3
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
- Deoxycorticosterone acetate
56-47-3
- US $0.00-0.00 / kg
- 99.1
- WUHAN FORTUNA CHEMICAL CO., LTD
- Deoxycorticosterone acetate
56-47-3
- US $46.00-36.00 / mg
- 99.81%
- TargetMol Chemicals Inc.
- corticosterone
56-47-3
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
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