ChemicalBook >> CAS DataBase List >>Deoxycorticosterone acetate
Deoxycorticosterone acetate
- CAS No.
- 56-47-3
- Chemical Name:
- Deoxycorticosterone acetate
- Synonyms
- doxo;DOCA;steraq;arcort;ocriten;syncort;cortate;percotol;syncorta;unidocan
- CBNumber:
- CB3462948
- Molecular Formula:
- C23H32O4
- Molecular Weight:
- 372.5
- MDL Number:
- MFCD00003660
- MOL File:
- 56-47-3.mol
Last updated:2024-11-19 23:02:33
| Melting point | 157°C |
|---|---|
| alpha | D20 +168 to +176° (dioxane) |
| Boiling point | 421.94°C (rough estimate) |
| Density | 1.0415 (rough estimate) |
| refractive index | 175 ° (C=1, Dioxane) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: insoluble |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 4mg/L(25 ºC) |
| Merck | 2901 |
| BRN | 2570798 |
| InChI | InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 |
| InChIKey | VPGRYOFKCNULNK-ACXQXYJUSA-N |
| SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2 |
| LogP | 3.080 |
| CAS DataBase Reference | 56-47-3(CAS DataBase Reference) |
| FDA UNII | 6E0A168OB8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H373-H360 |
| Precautionary statements | P260-P314-P501 |
| Safety Statements | 22-24/25 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
| RTECS | HG0525000 |
| HazardClass | IRRITANT |
| HS Code | 2937290000 |
Deoxycorticosterone acetate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 1g | $207 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1174001 | Deoxycorticosterone acetate United States Pharmacopeia (USP) Reference Standard | 56-47-3 | 200mg | $174.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 5g | $673 | 2024-03-01 | Buy |
| Sigma-Aldrich | D7000 | Deoxycorticosterone acetate | 56-47-3 | 25g | $1590 | 2024-03-01 | Buy |
| Sigma-Aldrich | D0400000 | Desoxycortone acetate European Pharmacopoeia (EP) Reference Standard | 56-47-3 | d0400000 | $220 | 2024-03-01 | Buy |
Deoxycorticosterone acetate Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Adrenocortical/mineralocorticoid Steroid.
Uses
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Definition
ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone.
brand name
Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].
General Description
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
Purification Methods
11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Deoxycorticosterone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 263)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2097 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
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| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
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| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
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| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from Deoxycorticosterone acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | Deoxycorticosterone acetate
56-47-3
|
US $0.00-0.00 / kg | 1kg | 99.1 | 100KG | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Deoxycorticosterone acetate
56-47-3
|
US $46.00-36.00 / mg | 99.81% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-08 | corticosterone
56-47-3
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- Deoxycorticosterone acetate
56-47-3
- US $0.00-0.00 / kg
- 99.1
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Deoxycorticosterone acetate
56-47-3
- US $46.00-36.00 / mg
- 99.81%
- TargetMol Chemicals Inc.
-
- corticosterone
56-47-3
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
56-47-3(Deoxycorticosterone acetate )Related Search:
1of4
deoxycortoneacetate
descorterone
descotone
desoxycorticosterone-21-acetate
dorcostrin
doxo
doxycamon
krinocorts
ocriten
organon’sdocaacetate
percorten
percotol
Pregn-4-en-21-ol-3,20-dione21-acetate
primocort
primocortan
sincortex
steraq
syncort
syncorta
syncortyl
4-pregnene-3,20-dione-21-olacetate
unidocan
11-deoxycorticosterone21-acetate
20-dione,21-hydroxy-pregn-4-ene-acetate
21-acetoxy-3,20-diketopregn-4-ene
21-Acetyloxypregn-4-ene-3,20-dione
21-hydroxypregn-4-ene-3,20-dione21-acetate
11-DEOXYCORTICOSTERONE ACETATE
11-desoxycorticosterone acetate
21-ACETOXYPROGESTERONE
21-ACETOXY-4-PREGNENE-3,20-DIONE
21-HYDROXY-4-PREGNENE-3,20-DIONE 21-ACETATE
21-HYDROXYPROGESTERONE 21-ACETATE
21-HYDROXYPROGESTERONE ACETATE
DESOXYCORTONE ACETATE
DESOXYCORTICOSTERONE ACETATE
DEOXYCORTICOSTERONE ACETATE
DELTA4-PREGNEN-21-OL-3, 20-DIONE ACETATE
CORTEXONE ACETATE
DOCA
DOC ACETATE
4-PREGNEN-21-OL-3,20-DIONE ACETATE
4-PREGNEN-21-OL-3,20-DIONE 21-ACETATE
Desoxycorticostisone acetate
21-HYDROXYPROGESTERONE 21-ACETATE VETRAN
11-Deoxycorticosterone acetate, 21-Acetoxy-4-pregnene-3,20-dione, 21-Acetoxyprogesterone, 21-Hydroxy-4-pregnene-3,20-dione 21-acetate, 21-Hydroxyprogesterone 21-acetate, 4-Pregnen-21-ol-3,20-dione 21-acetate, Cortexone acetate, DOC acetate
21-Acetoxypregn-4-en-3,20-dione
21-Hydroxypregn-4-ene-3,20-dione Acetate
Decorten
Decosteron
DEOXYCORTICOSTERONE ACETATE(RG)
Desoxycorticosterone Acetate (200 mg)
3,20-Dioxopregn-4-en-21-yl acetate
Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
DOCA(Deoxycorticosterone acetate)
arcort
bio-corten
cortacet