ChemicalBook >> CAS DataBase List >>(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide structure

CAS No.: 2098799-78-9

Chemical Name:: (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Synonyms: VHL ligand 7;VH 032, propargyl;(S,R,S)-AHPC-propargy;(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthia;(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

CBNumber:: CB34902516

Molecular Formula:: C27H34N4O5S

Molecular Weight:: 526.65

MDL Number:

MOL File:: 2098799-78-9.mol

Last updated:2024-07-02 08:55:06

Request For Quotation

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Properties

Boiling point	826.0±65.0 °C(Predicted)
Density	1.259±0.06 g/cm3(Predicted)
form	Solid
pka	13.29±0.46(Predicted)
color	White to off-white

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	6683	VH032,propargyl ≥95%(HPLC)	2098799-78-9	50	$477	2021-12-16	Buy

Product number	Packaging	Price	Buy
6683	50	$477	Buy

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Chemical Properties,Uses,Production

Biological Activity

VH 032, propargyl is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC? research and development; incorporates an E3 ligase ligand with terminal propargyl ready for conjugation to a target protein ligand.

storage

Store at -20°C

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Suppliers

Global( 24)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21669	55
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3152	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7176	65
Shanghai Jiyi Biological Technology Co., LTD	021-54135696 18516235431	shgegenetech@163.com	China	532	55
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3465	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7887	56
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9909	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
TargetMol Chemicals Inc.	58
Zhengzhou Lingzhiyue Technology Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
Daicel Chiral Technologies (China)CO.,LTD	65
Shanghai Jiyi Biological Technology Co., LTD	55
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Shanghai Chaolan Chemical Technology Center	58

VH 032, propargyl (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide VHL ligand 7 (2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthia (S,R,S)-AHPC-propargy 2098799-78-9