ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21)
- CAS No.
- Chemical Name:
- ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21)
- Synonyms
- ANTI-UCH-L1;Anti-Ubiquitin thioesterase L1;Anti-Neuron cytoplasmic protein 95;Anti-UCHL1 antibody produced in rabbit;ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21);Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1
- CBNumber:
- CB3494512
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD07370534
- MOL File:
- Mol file
ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA005993 | Anti-UCHL1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA005993 | Anti-UCHL1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy |
ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21) Chemical Properties,Uses,Production
Uses
Anti-UCHL1 antibody produced in rabbit has been used in:
- immunohistochemistry at 1:100 dilution
- immunofluorescence
- proximity ligation assay
- indirect immunolabeling at 1:1000 dilution
General Description
The ubiquitin C-terminal hydrolase L1 (UCH-L1) gene is mapped to human chromosome 4p13. The protein localized in the cytosol and nucleus. UCH-L1 protein is primarily expressed in neuroendocrine tissues, neurons and in testis/ovary. Rabbit polyclonal anti-UCHL1 antibody recognizes ubiquitin carboxyl-terminal hydrolase isozyme L1.
Biochem/physiol Actions
Ubiquitin C-terminal hydrolase-L1 (UCHL1) is a deubiquitinating enzyme (DUB) that hydrolyzes C-terminal ubiquitin esters and amides, and peptide?ubiquitin amides to ubiquitin monomers in- vitro. In addition to DUB activity, it also possesses E3 ubiquitin-protein ligase activity. UCHL1 is involved in the regulation of the ubiquitin-dependent proteolytic system. UCH-L1 plays a vital role in cancer development and progression by upstream activation of protein kinase B (Akt). Mutation in the UCHL1 gene is associated with the development of Parkinson′s disease (PD).
ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-UBIQUITIN-C-TERMINAL HYDROLASE L1 (TS-21) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6913 | 91 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |