ChemicalBook >> CAS DataBase List >>LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)

CAS No.
27244-64-0
Chemical Name:
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
Synonyms
6-Hydroxy-L-DOPA;(2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid;Topa;Levodopa Related CoMpound A;6-oh-dopa;Topaquinone;l-hydroxydopa;Hydroxy-L-dopa;l-6-hydroxydopa;6-Hydroxydopa, L-
CBNumber:
CB3501432
Molecular Formula:
C9H11NO5
Molecular Weight:
213.19
MDL Number:
MOL File:
27244-64-0.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Properties

Melting point >190°C (dec.)
Boiling point 515.2±38.0 °C(Predicted)
Density 1.606±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated)
pka 2.34±0.25(Predicted)
form Solid
color Brown to Black
Stability Air Sensitive, Hygroscopic
FDA UNII 580PK2O48O
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315
Precautionary statements  P264-P270-P280-P301+P312+P330-P332+P313-P501
HS Code  2922504500

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2095 Levodopa Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 27244-64-0 100mg $593 2024-03-01 Buy
Sigma-Aldrich 1361010 Levadopa Related Compound A 27244-64-0 50mg $1490 2024-03-01 Buy
TRC H941725 6-Hydroxy-L-DOPA 27244-64-0 25mg $190 2021-12-16 Buy
TRC H941725 6-Hydroxy-L-DOPA 27244-64-0 250mg $1480 2021-12-16 Buy
Product number Packaging Price Buy
PHR2095 100mg $593 Buy
1361010 50mg $1490 Buy
H941725 25mg $190 Buy
H941725 250mg $1480 Buy

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Chemical Properties,Uses,Production

Uses

6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.

Uses

6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.

Definition

ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6.

LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-dihydroxy-l-tyrosine 4,5-trihydroxyphenyl)-3-(l-alanin 6-oh-dopa l-2,4,5-trihydroxyphenylalanine l-6-hydroxydopa l-hydroxydopa LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) (S)-α-Amino-3,4,6-trihydroxybenzenepropanoic acid 2,4,5-Trihydroxy-L-phenylalanine Topaquinone 3-(3,4,6-Trihydroxyphenyl)-L-alanine Hydroxy-L-dopa 6-Hydroxy-L-DOPA (Levodopa Related CoMpound A) 3-(2,4,5-Trihydroxyphenyl)-L-alanine Levadopa Related Compound A Levodopa EP Impurity A 3-(3,4,6-Tirhydroxyphenyl)-alanine Levodopa Impurity 1 (Levodopa EP Impurity A) 6-Hydroxy L-DOPA (Levadopa Related Compound A) L-Tyrosine, 2,5-dihydroxy- (S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid Levodopa EP Impurity A/ Levodopa Related Compound A (2-Hydroxy Levodopa) 2-Hydroxy Levodopa Levodopa Related Compound A ((3-(2,4,5-Trihydroxyphenyl)-L-alanine) or (3-(3,4,6-Trihydroxyphenyl)a (1361010) Topa 6-Hydroxy-L-DOPA Levodopa Related CoMpound A (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid 6-Hydroxydopa, L- Levodopa EP Impurity A Levodopa USP Related Compound A Levodopa EP Impurity A (Levodopa USP Related Compound A, 6-Hydroxy L-DOPA) 27244-64-0 Amino Acids & Derivatives, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals