OXIDIZED NIFEDIPINE
- CAS No.
- 67035-22-7
- Chemical Name:
- OXIDIZED NIFEDIPINE
- Synonyms
- B 4759;BAY-b-4759;Nifedipine-1;Dehydro Nifedipine;NIFEDIPINE EP IMP A;Nifidipine Impurity A;Nitrophenyl nifedipine;Nifedipine impurity A CRS;Nifedipine impurity A (EP);Divalproex Sodium Impurity 1
- CBNumber:
- CB3505238
- Molecular Formula:
- C17H16N2O6
- Molecular Weight:
- 344.32
- MDL Number:
- MFCD00153847
- MOL File:
- 67035-22-7.mol
- MSDS File:
- SDS
Melting point | 100-105 °C |
---|---|
Boiling point | 443.7±45.0 °C(Predicted) |
Density | 1.284±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | powder |
pka | 1.55±0.29(Predicted) |
color | yellow |
FDA UNII | OR3W8GT1C8 |
EPA Substance Registry System | 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester (67035-22-7) |
UNSPSC Code | 41116107 |
NACRES | NA.77 |
OXIDIZED NIFEDIPINE price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | UC167 | Oxidized Nifedipine powder, ~95% (HPLC) | 67035-22-7 | 5mg | $469 | 2024-03-01 | Buy |
Sigma-Aldrich | 1463600 | Nifedipine Nitrophenylpyridine Analog United States Pharmacopeia (USP) Reference Standard | 67035-22-7 | 25mg | $1530 | 2024-03-01 | Buy |
Cayman Chemical | 23229 | Dehydro Nifedipine ≥98% | 67035-22-7 | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 23229 | Dehydro Nifedipine ≥98% | 67035-22-7 | 5mg | $193 | 2024-03-01 | Buy |
Sigma-Aldrich | UC167 | Oxidized Nifedipine powder, ~95% (HPLC) | 67035-22-7 | 10mg | $861 | 2024-03-01 | Buy |
OXIDIZED NIFEDIPINE Chemical Properties,Uses,Production
Description
Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.
Chemical Properties
Pale Yellow Solid
Uses
Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.
Uses
The main Nifedipine metabolite in human plasma
Definition
ChEBI: Dehydronifedipine is a phenylpyridine.
Biochem/physiol Actions
CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.
OXIDIZED NIFEDIPINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19825 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3883 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11922 | 58 |
View Lastest Price from OXIDIZED NIFEDIPINE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-11-16 | Dehydro Nifedipine
67035-22-7
|
US $50.00-188.00 / mg | 98.65% | 10g | TargetMol Chemicals Inc. | ||
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2019-12-29 | Oxidized Nifedipine
67035-22-7
|
US $0.10 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Dehydro Nifedipine
67035-22-7
- US $50.00-188.00 / mg
- 98.65%
- TargetMol Chemicals Inc.
-
- Oxidized Nifedipine
67035-22-7
- US $0.10 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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