ChemicalBook >> CAS DataBase List >>Methyl (4-bromobenzoyl)-L-cysteinate

Methyl (4-bromobenzoyl)-L-cysteinate

CAS No.
1947408-74-3
Chemical Name:
Methyl (4-bromobenzoyl)-L-cysteinate
Synonyms
Cysteine thiol probe, 10 mM in DMSO;Methyl (4-bromobenzoyl)-L-cysteinate;L-Cysteine, N-(4-bromobenzoyl)-, methyl ester;pharmacophore,inhibit,Cysteine thiol probe,products,enone-based,chromophore,thiol-based,electrophilic,Inhibitor,l-cystine,Natural
CBNumber:
CB35542274
Molecular Formula:
C11H12BrNO3S
Molecular Weight:
318.19
MDL Number:
MOL File:
1947408-74-3.mol
Last updated:2025-01-27 09:38:02

Methyl (4-bromobenzoyl)-L-cysteinate Properties

Boiling point 465.2±45.0 °C(Predicted)
Density 1.491±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 250 mg/mL (785.69 mM)
pka 9.05±0.10(Predicted)
form Solid
color White to off-white
UNSPSC Code 12352101

Methyl (4-bromobenzoyl)-L-cysteinate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 907243 Methyl (4-bromobenzoyl)-L-cysteinate ≥95% 1947408-74-3 100mg $346 2023-06-20 Buy
DC Chemicals 012836 Cysteinethiolprobe 1947408-74-3 003 $1700 2021-12-16 Buy
Product number Packaging Price Buy
907243 100mg $346 Buy
012836 003 $1700 Buy

Methyl (4-bromobenzoyl)-L-cysteinate Chemical Properties,Uses,Production

Uses

Methyl (4-bromobenzoyl)-L-cysteinate is a chemoselective thiol probe for detection of electrophilic metabolites. As it is often difficult to isolate low-abundance natural products from extracts, metabolities with bioactivity or therapeutic potential may be missed. Castro-Falcón, et al developed a reactivity-guided approach using thiolate probes to discover electrophilic natural products - a cysteine-based probe and thiophenol-based probe. Both consist of

  • A chemoselective reagent for covalent reactivity with a pharmacophore,
  • A conspicuous UV/VIS or mass spectrometric (MS) tag,
  • A linker between the tag and reagent. Methyl (4-bromobenzoyl)-L-cysteinate contains a bromine MS tag and phenyl bromide UV tag that was demonstrated to chemoselectively label enone-, β-lactam-, and β-lactone-based natural products.

Complementarily, a thiophenol probe (cat# 125237) with a chlorine MS tag and phenyl chloride UV tag labeled epoxide-based natural products. These probes can be used in diverse extracts (bacterial, fungal, plant) to chemically faciliate access to high-value metabolites.

Methyl (4-bromobenzoyl)-L-cysteinate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl (4-bromobenzoyl)-L-cysteinate Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Changzhou Jiezhan Chemical Technology Co., Ltd 15861130028; 15861130028 956912955@qq.com China 288 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Changzhou Xuanye Technology Co., Ltd 15195022192 279776773@qq.com China 2011 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58

View Lastest Price from Methyl (4-bromobenzoyl)-L-cysteinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cysteine thiol probe pictures 2024-11-09 Cysteine thiol probe
1947408-74-3
US $32.00-72.00 / mg 98.46% 10g TargetMol Chemicals Inc.

Methyl (4-bromobenzoyl)-L-cysteinate Spectrum

Methyl (4-bromobenzoyl)-L-cysteinate pharmacophore,inhibit,Cysteine thiol probe,products,enone-based,chromophore,thiol-based,electrophilic,Inhibitor,l-cystine,Natural L-Cysteine, N-(4-bromobenzoyl)-, methyl ester Cysteine thiol probe, 10 mM in DMSO 1947408-74-3