ChemicalBook >> CAS DataBase List >>ML401
ML401
- CAS No.
- 1597489-14-9
- Chemical Name:
- ML401
- Synonyms
- ML401;CID73169083;ML401 (CID73169083);ML401, 10 mM in DMSO;ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401;(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one;(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
- CBNumber:
- CB35559120
- Molecular Formula:
- C20H20BrClN2O
- Molecular Weight:
- 419.74
- MDL Number:
- MOL File:
- 1597489-14-9.mol
Last updated:2025-04-17 18:22:24
ML401 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0066585 | ML401 99.87% | 1597489-14-9 | 5mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0066585 | ML401 99.87% | 1597489-14-9 | 10mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-0066585 | ML401 99.87% | 1597489-14-9 | 25mg | $990 | 2021-12-16 | Buy |
| ChemScene | CS-0066585 | ML401 99.87% | 1597489-14-9 | 50mg | $1650 | 2021-12-16 | Buy |
| ChemScene | CS-0066585 | ML401 99.87% | 1597489-14-9 | 100mg | $2250 | 2021-12-16 | Buy |
ML401 Chemical Properties,Uses,Production
Uses
ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].
in vivo
ML401 shows very good stability in both human plasma and mouse plasma[1].
References
[1] Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet]. PMID:25834900
ML401 Preparation Products And Raw materials
Raw materials
Preparation Products
ML401 Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4601 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Shanghai SuperLan Chemcial Technique Centre | 021-2022843681 15618226720 | lucy@atkchemical.com | China | 10123 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29763 | 68 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
ML401
CID73169083
2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one
ML401 (CID73169083)
ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401
(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one
ML401, 10 mM in DMSO
1597489-14-9
C20H20BrClN2O