TOFISOPAM
- CAS No.
- 22345-47-7
- Chemical Name:
- TOFISOPAM
- Synonyms
- SERIEL;Tosopam;EGYT 341;grandaxin;tofizopam;TOFISOPAM;Tofisopam, >=99%;TOFISOPAM 22345-47-7;7-CHLORO-1-METHYL-5-PHENYL-1,5-BENZODIAZEPINE-2,4-DIONE;-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine
- CBNumber:
- CB3738807
- Molecular Formula:
- C22H26N2O4
- Molecular Weight:
- 382.45
- MDL Number:
- MFCD00823171
- MOL File:
- 22345-47-7.mol
Melting point | 155-159°C |
---|---|
Boiling point | 509.61°C (rough estimate) |
Density | 1.2098 (rough estimate) |
refractive index | 1.6500 (estimate) |
solubility | DMSO: ~14 mg/mL |
pka | 7.29±0.40(Predicted) |
form | solid |
color | white |
λmax | 310nm(MeOH)(lit.) |
Merck | 14,9503 |
Stability | Hygroscopic |
FDA UNII | UZC80HAU42 |
ATC code | N05BA23 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS09 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H400 | |||||||||
Precautionary statements | P273-P301+P312+P330 | |||||||||
Hazard Codes | Xn,N | |||||||||
Risk Statements | 22-50 | |||||||||
Safety Statements | 60-61 | |||||||||
RIDADR | UN 3077 9/PG 3 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | DE9540000 | |||||||||
HS Code | 2933.99.8290 | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
NFPA 704 |
|
TOFISOPAM price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T8200 | Tofisopam ≥98% (HPLC), solid | 22345-47-7 | 10mg | $176 | 2024-03-01 | Buy |
Sigma-Aldrich | T8200 | Tofisopam ≥98% (HPLC), solid | 22345-47-7 | 50mg | $558 | 2024-03-01 | Buy |
TCI Chemical | T3509 | Tofisopam >98.0%(HPLC) | 22345-47-7 | 50mg | $84 | 2024-03-01 | Buy |
TCI Chemical | T3509 | Tofisopam >98.0%(HPLC) | 22345-47-7 | 250mg | $253 | 2024-03-01 | Buy |
Cayman Chemical | 22026 | Tofisopam ≥95% | 22345-47-7 | 1mg | $73 | 2024-03-01 | Buy |
TOFISOPAM Chemical Properties,Uses,Production
Originator
Grandaxine,Ozothine,France,1975
Uses
Tofisopam is a reagent used in preparation of allosteric ligands for pharmacological dark receptors GPR68 and GPR65. An anticonvulsant.
Definition
ChEBI: Tofisopam is an organic molecular entity.
Manufacturing Process
A mixture of 38.6 g (0.1 mol) of 3,4,3',4'-tetramethoxy-6-(α-acetopropyl)- benzophenone, 5.5 g (0.11 mol) of 100% hydrazine hydrate or 3.52 g (0.11 mol) of hydrazine, and 500 ml of absolute ethanol is boiled for 5 hours. After adding 100 ml of benzene, 400 ml of solvent mixture is distilled off from the reaction mixture by slow boiling for 3 hours. After cooling for 8 hours, 19 g of 5H-2,3-benzodiazepine derivative are separated from the residue as small, white crystals. The melting point is 133°C to 136°C (after recrystallizing from absolute ethanol, 136°C)
Therapeutic Function
Tranquilizer
TOFISOPAM Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29899 | 58 |
Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 906 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49403 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15370 | 58 |
Shijiazhuang Tongyang Import and Export Co., LTD | 18031361688; | admin@sjztongyang.com | China | 987 | 58 |
changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9740 | 58 |
View Lastest Price from TOFISOPAM manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-08-11 | TOFISOPAM
22345-47-7
|
US $10.00 / KG | 1g | 99 | 100kg/kg | Shijiazhuang tongyang Import and Export Co., LTD | ||
2019-07-31 | TOFISOPAM 22345-47-7
22345-47-7
|
US $1.00 / g | 1g | 99% | 300 Ton/Tons per Month china raw material pharmaceutical Tofisopam | Cangzhou Wanyou New Material Technology Co.,Ltd | ||
2019-07-06 | TOFISOPAM
22345-47-7
|
US $14.00 / KG | 1KG | 98% | 50KG | Career Henan Chemical Co |
- TOFISOPAM
22345-47-7
- US $10.00 / KG
- 99
- Shijiazhuang tongyang Import and Export Co., LTD
- TOFISOPAM 22345-47-7
22345-47-7
- US $1.00 / g
- 99%
- Cangzhou Wanyou New Material Technology Co.,Ltd
- TOFISOPAM
22345-47-7
- US $14.00 / KG
- 98%
- Career Henan Chemical Co