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Procyanidin B1

CAS No.
20315-25-7
Chemical Name:
Procyanidin B1
Synonyms
Proanthocyanidin B1;Procyanidin B1, 97%, from Vitis vinifera Linn.;OligoMeric Proantho Cyanidins;PROCYANIDIN B1;Procyanidin B1-RM;PROCYANIDIN A2(SH);PROCYANIDIN B1(RG);PROCYANIDINDIMERB1;(4→8)-Procyanidin B1;Procyanidin Impurity 2
CBNumber:
CB3753343
Molecular Formula:
C30H26O12
Molecular Weight:
578.52
MDL Number:
MFCD01861512
MOL File:
20315-25-7.mol
Last updated:2024-11-19 23:02:33

Procyanidin B1 Properties

Melting point 231~232℃
Boiling point 955.3±65.0 °C(Predicted)
Density 1.705±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility Acetone (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
pka 9.29±0.60(Predicted)
form Solid
color Pale Brown
InChIKey XFZJEEAOWLFHDH-UKWJTHFESA-N
LogP 0.300 (est)
FDA UNII 0566J48E7X

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
10-23
HS Code  29329990

Procyanidin B1 price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89764 Procyanidin B1 phyproof? Reference Substance 20315-25-7 5MG $387 2024-03-01 Buy
Sigma-Aldrich 19542 Procyanidin B1 analytical standard 20315-25-7 1mg $573 2024-03-01 Buy
Cayman Chemical 22411 Procyanidin B1 ≥98% 20315-25-7 1mg $59 2024-03-01 Buy
Cayman Chemical 22411 Procyanidin B1 ≥98% 20315-25-7 5mg $239 2024-03-01 Buy
Cayman Chemical 22411 Procyanidin B1 ≥98% 20315-25-7 10mg $448 2024-03-01 Buy
Product number Packaging Price Buy
PHL89764 5MG $387 Buy
19542 1mg $573 Buy
22411 1mg $59 Buy
22411 5mg $239 Buy
22411 10mg $448 Buy

Procyanidin B1 Chemical Properties,Uses,Production

Description

Procyanidin B1 is a polyphenol flavonoid existing as a dimer of (+)-catechin and (−)-epicatechin . It inhibits hepatitis C virus RNA replication (EC50 = 72 μM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 μM. Procyanidin B1 (10 μg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells. It decreases TNF-α, phosphorylated p38 MAPK, and NF-κB levels following LPS administration.

Uses

Procyanidins B1 is a B type proanthocyanidins found in ceylon cinnamon and is known to exhibit anti-inflammatory effects.

Definition

ChEBI: Procyanidin B1 is a proanthocyanidin consisting of (-)-epicatechin and (+)-catechin units joined by a bond between positions 4 and 8' respectively in a beta-configuration.. Procyanidin B1 can be found in Cinnamomum verum (Ceylon cinnamon, in the rind, bark or cortex), in Uncaria guianensis (cat's claw, in the root), and in Vitis vinifera (common grape vine, in the leaf) or in peach. It has a role as a metabolite, an EC 3.4.21.5 (thrombin) inhibitor and an anti-inflammatory agent. It is a hydroxyflavan, a proanthocyanidin, a biflavonoid and a polyphenol. It is functionally related to a (-)-epicatechin and a (+)-catechin.

154-23-4
20315-25-7
Synthesis of Procyanidin B1 from Cianidanol
Global( 221)Suppliers
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Shanghai Zheyan Biotech Co., Ltd.
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View Lastest Price from Procyanidin B1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Procyanidin B1 pictures 2024-11-19 Procyanidin B1
20315-25-7
US $47.00-289.00 / mg 99.13% 10g TargetMol Chemicals Inc.
Procyanidin B1 pictures 2024-04-13 Procyanidin B1
20315-25-7
US $10.00-30.00 / kg 1kg 99% 100ton/ month Nanjing Deda New Material Technology Ltd.
Procyanidin B1  pictures 2023-02-24 Procyanidin B1
20315-25-7
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Procyanidin B1 pictures
  • Procyanidin B1
    20315-25-7
  • US $47.00-289.00 / mg
  • 99.13%
  • TargetMol Chemicals Inc.
  • Procyanidin B1 pictures
  • Procyanidin B1
    20315-25-7
  • US $10.00-30.00 / kg
  • 99%
  • Nanjing Deda New Material Technology Ltd.
  • Procyanidin B1  pictures
  • Procyanidin B1
    20315-25-7
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
Procyanidin B1 [Epicatechin (4β→8) catechin] PROCYANIDIN B1 CIS,TRANS''-4,8''-BI-(3,3',4',5,7-PENTAHYDROXYFLAVANE) EPICATECHIN(4B-8)CATECHIN EPICATECHIN(4BETA->8)CATECHIN (2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-4,8'-bichroman-3,3',5,5',7,7'-hexol (2R,2'R,3R,3'S,4β)-3,3',4,4'-Tetrahydro-2α,2'α-bis(3,4-dihydroxyphenyl)-4,8'-bi[2H-1-benzopyran]-3,3',5,5',7,7'-hexol (2R,3R,4R,2'R,3'S)-2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-4,8'-bi(2H-1-benzopyran)-3,3',5,5',7,7'-hexol (4→8)-Procyanidin B1 2-(3,4-dihydroxyphenyl)-4-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-3,4-dihydro-2H-chromene-3,5,7-triol 2-(3,4-dihydroxyphenyl)-4-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-8-yl]chromane-3,5,7-triol PROCYANIDIN A2(SH) Procyanidin B1,cis,trans′′-4,8′′-Bi-(3,3′,4′,5,7-Pentahydroxyflavane) 2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol PROCYANIDIN B1(RG) PROCYANIDINDIMERB1 Procyanidin B1, froM Vitis vinifera Linn. Procyanidin Impurity 2 [4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-, (2R,2'R,3R,3'S,4R)- PROCYANIDIN B1 USP/EP/BP Proanthocyanidin B1 OligoMeric Proantho Cyanidins Procyanidin B1, 97%, from Vitis vinifera Linn. (2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol (2R,2'R,3R,3'S,4R)-2,2'-Bis(3,4-dihydroxyphenyl)-[4,8'-bichromane]-3,3',5,5',7,7'-hexaol 2,2'-Bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol Procyanidin B1-RM 20315-25-7 Analytical Standards Alphabetic Analytical Chromatography Product Catalog PON - PT Catechins & Tannins chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract