1H-1,2,4-Triazole-3,5-diamine
- CAS No.
- 1455-77-2
- Chemical Name:
- 1H-1,2,4-Triazole-3,5-diamine
- Synonyms
- 3,5-DIAMINO-1,2,4-TRIAZOLE;GUANAZOLE;4H-1,2,4-TRIAZOLE-3,5-DIAMINE;nsc1895;NSC 1895;MC 51762;NCI-C04819;TIMTEC-BB SBB004371;3,5-diamino-s-triazol;Guanazole (VAN) (8CI)
- CBNumber:
- CB3756001
- Molecular Formula:
- C2H5N5
- Molecular Weight:
- 99.09
- MDL Number:
- MFCD00005233
- MOL File:
- 1455-77-2.mol
- MSDS File:
- SDS
Melting point | 202-205 °C (lit.) |
---|---|
Boiling point | 473.7±28.0 °C(Predicted) |
Density | 1.686±0.06 g/cm3(Predicted) |
refractive index | 1.7330 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | H2O: clear to hazy |
form | powder |
pka | 12.10±0.40(Predicted) |
color | white |
Water Solubility | Soluble in water. |
BRN | 112467 |
Stability | Stability Air sensitive. Reacts with acids and oxidizing agents. |
InChIKey | PKWIYNIDEDLDCJ-UHFFFAOYSA-N |
CAS DataBase Reference | 1455-77-2(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | I01TWM5267 |
NCI Drug Dictionary | guanazole |
NIST Chemistry Reference | 3,5-Diamino-1,2,4-triazole(1455-77-2) |
EPA Substance Registry System | Guanazole (1455-77-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08,GHS09 |
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Signal word | Warning | |||||||||
Hazard statements | H361fd-H373-H411 | |||||||||
Precautionary statements | P202-P260-P273-P280-P308+P313-P391 | |||||||||
Hazard Codes | Xn,Xi,C | |||||||||
Risk Statements | 22-34 | |||||||||
Safety Statements | 36/37-45-36/37/39-27-26 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | XZ4535000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29339990 | |||||||||
NFPA 704 |
|
1H-1,2,4-Triazole-3,5-diamine price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D26202 | 3,5-Diamino-1,2,4-triazole 98% | 1455-77-2 | 25g | $189 | 2024-03-01 | Buy |
Sigma-Aldrich | D26202 | 3,5-Diamino-1,2,4-triazole 98% | 1455-77-2 | 100g | $683 | 2024-03-01 | Buy |
TCI Chemical | D2587 | 3,5-Diamino-1,2,4-triazole >97.0%(T) | 1455-77-2 | 5g | $32 | 2024-03-01 | Buy |
TCI Chemical | D2587 | 3,5-Diamino-1,2,4-triazole >97.0%(T) | 1455-77-2 | 25g | $128 | 2024-03-01 | Buy |
Alfa Aesar | B22775 | 3,5-Diamino-1,2,4-triazole, 98+% | 1455-77-2 | 5g | $33.65 | 2024-03-01 | Buy |
1H-1,2,4-Triazole-3,5-diamine Chemical Properties,Uses,Production
Chemical Properties
colourless crystals or faintly yellow powder
Uses
3,5-Diamino-1,2,4-triazole is used as an inhibitor of DNA synthesis. It also serves as an antitumor agents in the treatment of epigenetically-based diseases. It acts as a corrosion inhibitor for copper.
Definition
ChEBI: An aromatic amine that is 1,2,4-triazole substituted at positions 3 and 5 by amino groups.
General Description
Colorless crystals.
Air & Water Reactions
1H-1,2,4-Triazole-3,5-diamine is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble.
Reactivity Profile
The triazoles, of which 1H-1,2,4-Triazole-3,5-diamine is a member, are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type of substitution to the triazole ring. The amine substituted derivatives, 1H-1,2,4-Triazole-3,5-diamine, tend not to be explosion sensitive. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. 1H-1,2,4-Triazole-3,5-diamine forms salts readily with acids.
Health Hazard
SYMPTOMS: 1H-1,2,4-Triazole-3,5-diamine is stable under normal laboratory conditions.
Fire Hazard
Flash point data for 1H-1,2,4-Triazole-3,5-diamine are not available. 1H-1,2,4-Triazole-3,5-diamine is probably combustible.
Safety Profile
Human systemic effects by intravenous route: leukopenia (reduced white blood cell count) and thrombo cytopenia (reduced blood platelet count). Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
The triazole crystallises from water or EtOH. [Beilstein 26 III/IV 1161.]
1H-1,2,4-Triazole-3,5-diamine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12841 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10310 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17453 | 58 |
View Lastest Price from 1H-1,2,4-Triazole-3,5-diamine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-25 | 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
|
US $20.00-1.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2024-10-24 | 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | ||
2024-10-11 | 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
- 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
- 1H-1,2,4-Triazole-3,5-diamine
1455-77-2
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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