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Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester

CAS No.
154773-33-8
Chemical Name:
Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester
Synonyms
CBNumber:
CB38382622
Molecular Formula:
C8H16O5
Molecular Weight:
192.21
MDL Number:
MOL File:
154773-33-8.mol
Last updated:2023-02-23 14:24:01

Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester Properties

Boiling point 286.4±20.0 °C(Predicted)
Density 1.102±0.06 g/cm3(Predicted)
pka 14.35±0.10(Predicted)

Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester Chemical Properties,Uses,Production

Biological Activity

PEG2-ethyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]-, ethyl ester Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28819 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
154773-33-8