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1-(2-Furoyl)piperazine

1-(2-Furoyl)piperazine structure

CAS No.: 40172-95-0

Chemical Name:: 1-(2-Furoyl)piperazine

Synonyms: AKOS BB/0087;AKOS B003992;AKOS BBS-00003689;BIO-FARMA BF003584;TIMTEC-BB SBB003747;RARECHEM AH CK 0108;N-Furoyl piperazine;2-furoic piperazide;Terazosin Impurity10;2-(2-FUROYL)PIPERAZINE

CBNumber:: CB3853599

Molecular Formula:: C9H12N2O2

Molecular Weight:: 180.2

MDL Number:: MFCD00038831

MOL File:: 40172-95-0.mol

Last updated:2025-01-27 09:38:02

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1-(2-Furoyl)piperazine Properties

Melting point	67-70 °C(lit.)
Boiling point	137-140°C 0,1mm
Density	1.1819 (rough estimate)
refractive index	1.5373 (estimate)
Flash point	>230 °F
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Chloroform, Methanol (Slightly)
pka	8.37±0.10(Predicted)
color	White to Pale Yellow
Sensitive	Hygroscopic
BRN	880196
Stability	Very Hygroscopic
CAS DataBase Reference	40172-95-0(CAS DataBase Reference)
FDA UNII	8AUX72LL1P
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

10-34

HazardClass

IRRITANT

HS Code

29339900

NFPA 704

	1
3		0

1-(2-Furoyl)piperazine price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3100	Prazosin Related Compound D certified reference material, pharmaceutical secondary standard	40172-95-0	50MG	$485	2024-03-01	Buy
Sigma-Aldrich	558966	1-(2-Furoyl)piperazine 97%	40172-95-0	25g	$133	2023-06-20	Buy
Sigma-Aldrich	Y0000623	Terazosin impurity L European Pharmacopoeia (EP) Reference Standard	40172-95-0	y0000623	$149	2023-01-07	Buy
Alfa Aesar	A16773	1-(2-Furoyl)piperazine, 98%	40172-95-0	25g	$65.5	2021-12-16	Buy
Alfa Aesar	A16773	1-(2-Furoyl)piperazine, 98%	40172-95-0	100g	$188	2021-12-16	Buy

Product number	Packaging	Price	Buy
PHR3100	50MG	$485	Buy
558966	25g	$133	Buy
Y0000623	y0000623	$149	Buy
A16773	25g	$65.5	Buy
A16773	100g	$188	Buy

1-(2-Furoyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow solid

Uses

1-(2-Furoyl)piperazine may be used to synthesize:

2-[4-(2-furoyl) piperazin-1-yl]-4-amino-6-benzyloxy-7-methoxyquinazoline hydrochloride monohydrate
2-[4-(2-furoyl)piperazin-1-yl]-4-amino-7-benzyloxy-6-methoxyquinazoline hydrochloride monohydrate
4-amino-2-[4-(2-furoyl)piperazin-1-yl]-quinazoline hydrochloride
6,7-dimethoxy-2-[4-(2-furoyl)-piperazin-1-yl]quinazoline-4-one hydrate
1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-furoyl)-piperazine hydrogen oxalate
1-(3,4-dichlorobenzyl)-4-(2-furoyl)-piperazine hydrogen oxalate
4-(9-fluorenyl)-1-(2-furoyl)piperazine
2-[4-(2-furoyl)piperazin-1-yl]-benzimidazole hydrochloride hydrate

Uses

2-Furanyl-1-piperazinylmethanone was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Uses

2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031

1-(2-Furoyl)piperazine Preparation Products And Raw materials

Raw materials

2-Furoic acid Toluene Di-tert-butyl dicarbonate Triethylamine Piperazine

Dichloromethane Sodium hydroxide Thionyl chloride

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Preparation Products

Prazosin

1-(2-Furoyl)piperazine Suppliers

Global( 260)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29792	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21632	55
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1376	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29871	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49476	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8840	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17365	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58

View Lastest Price from 1-(2-Furoyl)piperazine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-02	1-(2-Furoyl)piperazine 40172-95-0	US $1.00 / KG	1KG	98%	200kg	Career Henan Chemical Co

1-(2-Furoyl)piperazine
40172-95-0
US $1.00 / KG
98%
Career Henan Chemical Co

1-(2-Furoyl)piperazine Spectrum

1-(2-Furoyl)piperazine(40172-95-0)IR

40172-95-0(1-(2-Furoyl)piperazine)Related Search:

N-Aminoethylpiperazine 2-Ethylhexyl ferulate Piperazine Piperacillin 1-(Tetrahydro-2-Furoyl)Piperazine,TerazosinHcl,,1-(TETRAHYDRO-2-FUROYL)PIPERAZINE,N-(TETRAHYDRO-2-FUROYL)-PIPERAZINE

1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine monohydrochloride Terazosin impurity 2-Piperazine-4-amino-6,7-dimethoxyquinazoline (R)-Terazosin 2,2'-(1,4-Piperazinediyl)bis[6,7-diMethoxy-4-quinazolinaMine]

1-[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone 6,7-DiMethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one Terazosin EP IMpurity D [4-(4-AMino-7-hydroxy-6-Methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)Methanone NSC 351869

[4-(4-AMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-Methyl-2-furanyl]Methanone Terazosin hydrochloride dihydrate Terazosin IMpurity J

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BIO-FARMA BF003584 (FURAN-2-YL)(PIPERAZIN-1-YL)METHANONE 1-(2-FURANYLCARBONYL)-PIPERAZINE 1-(2-FUROYL)PIPERAZINE AKOS BBS-00003689 AKOS B003992 AKOS BB/0087 N-(2-FUROYL)PIPERAZINE RARECHEM AH CK 0108 TIMTEC-BB SBB003747 2-(2-FUROYL)PIPERAZINE N-Furoyl piperazine 1-(2-FUROYL)-PIPERAZINE 97% 2-furoic piperazide 1-(2-Furoyl)piperazine,98% Piperazine, 1-(2-furanylcarbonyl)- (2-Furyl)(piperazino) ketone Piperazino 2-furyl ketone Piperazino(2-furanyl) ketone Piperazino(2-furyl) ketone 1-(2-Furoyl)-piperazine ,97% Prazosin EP IMpurity D 2-Furanyl-1-piperazinylmethanone 1-(2-Furoyl)piperazine96% N-(2-Furoyl) piperazine 1-(2-Furoyl) piperazine Terazosin EP Impurity L Terazosin Impurity 12(Terazosin EP Impurity L) Terazosin Impurity10 Prazosin Impurity 4(Prazosin EP Impurity D) 1-(furan-2-carbonyl)piperazine Terazosin EP Impurity L (Prazosin EP Impurity D) Prazosin EP Impurity D (Terazosin EP Impurity L) Methanone, 2-furanyl-1-piperazinyl- 40172-95-0 1-(2-Furoyl)piperazine Terazosin Hydrochloride Dihydrate EP Impurity L 40172-95-0 Heterocyclic Building Blocks Piperazines Building Blocks BUILDING BLOCKS API intermediates Piperidines, Piperidones, Piperazines