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tert-Butyl rosuvastatin

CAS No.
355806-00-7
Chemical Name:
tert-Butyl rosuvastatin
Synonyms
Rosuvastatin tert-butyl ester;Rosuvastatin t-Butyl Ester;tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate;(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester;ZD-8;R1.5;tert-Butyl rosuvasta;ert-Butylrosuvastatin;dihydroxyhept-6-enoate;Rosuvastatin tert-butyl
CBNumber:
CB3855018
Molecular Formula:
C26H36FN3O6S
Molecular Weight:
537.64
MDL Number:
MFCD08460212
MOL File:
355806-00-7.mol
Last updated:2023-07-11 16:12:39

tert-Butyl rosuvastatin Properties

Melting point 136-138oC
Boiling point 704.2±70.0 °C(Predicted)
Density 1.259
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka 13.38±0.20(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
CAS DataBase Reference 355806-00-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

tert-Butyl rosuvastatin price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC R700540 Rosuvastatintert-ButylEster 355806-00-7 100mg $175 2021-12-16 Buy
Usbiological 290783 Tert-Butyl Rosuvastatin 355806-00-7 50g $545 2021-12-16 Buy
Matrix Scientific 093655 (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester 95+% 355806-00-7 5g $756 2021-12-16 Buy
Medical Isotopes, Inc. 52968 Rosuvastatintert-ButylEster 355806-00-7 1g $2120 2021-12-16 Buy
Matrix Scientific 093655 (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester 95+% 355806-00-7 1g $284 2021-12-16 Buy
Product number Packaging Price Buy
R700540 100mg $175 Buy
290783 50g $545 Buy
093655 5g $756 Buy
52968 1g $2120 Buy
093655 1g $284 Buy

tert-Butyl rosuvastatin Chemical Properties,Uses,Production

Uses

Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.

Uses

tert-Butyl Rosuvastatin is an impurity of Rosuvastatin (287714-41-4 #CAS), which is a HMG-?CoA reductase inhibitor. In combination of pemafibrate or a salt, it can function as cardiovascular disease medication.

289042-12-2
355806-00-7
Synthesis of tert-Butyl rosuvastatin from tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Global( 206)Suppliers
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Hangzhou ICH Biofarm Co., Ltd
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Capot Chemical Co.,Ltd.
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Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58

View Lastest Price from tert-Butyl rosuvastatin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-Butyl rosuvastatin pictures 2024-11-27 tert-Butyl rosuvastatin
355806-00-7
US $0.00 / Kg/Drum 1KG 99%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
tert-Butyl rosuvastatin pictures 2023-11-01 tert-Butyl rosuvastatin
355806-00-7
US $0.00-0.00 / KG 1KG 98% 200 Hangzhou ICH Biofarm Co., Ltd
tert-Butyl rosuvastatin pictures 2022-02-25 tert-Butyl rosuvastatin
355806-00-7
US $5.60 / KG 1KG 99% 1000tons Hong Kong Tiansheng New Material Trading Co., Ltd
(+)-(3R, 5S)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHANESULFONYLAMINO)PYRIMIDIN-5-YL]-(3, 5)-DIHYDROXY-6(E)-HEPTENOATE Rosuvastatin intermediate R-3 tert-Butyl(+)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesul fonylamino)pyrimidin-5-yl]-3,5-Dihydroxy-6(E)-Heptenoate ZD-8 Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N- methylsulfonylamino)pyrimidine-5-yl] -(3R,5S) -dihydroxy -(E)-6-Heptena Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R,5S)-dihydroxy (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)]-2-[Methyl(Methylsulfonyl)aMino-5-pyriMidinyl]-3,5-dihydroxy-6-heptenoicacidtert-butylester T-BUTYL 7-[4-(4-FLUOROPHENYL)-6-ISO-PROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL] -(3R,5S)-DIHYDROXY-(E)-6-HEPTENATE tert-Butyl rosuvasta Rosuvastatin calciuM interMediate R-3 (3R,5S,6E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL) METHYL AMINO]PYRIMIDIN-5-YL Rosuvastatin Acid t-Butyl Ester (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3, tert-Butyl Rosuvastatin (Rosuvastatin IMpurity) Rosuvastatin tert-butyl (+)-(3r, 5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5-Dihydroxy-6(E)-Heptenate (R1.5 Or T-Butyl-Rosuvastatin) R-1.5: (+)-(3R, 5S), TERT-BUTYL 7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYLSULPHONYLAMINO)-PYRIMIDINE-5-YL]-3, 5-DIHYDROXY-6(E)-HEPTENATE (E) - (3R,5S)-7-{4-(4-FLUOROPHENYL)-6-ISOPROPYL-2{METHYL SULPHONYLAMINO)] PYRIMIDIN-5-YL}-3,5-DIHYDROXYHEPTEN6-6 OICACID tert-butyl rosuvastatin dihydroxyhept-6-enoate 7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid t-butyl ester tert-butyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N- methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept- 6-enoate Rosuvatatin Impurity 22 Rosuvastatin Impurity 77 Rosuvastatin calcium-001 Rosuvastatin calcium-001-3R5S Rosuvastatin Impurity 20 (tert-Butyl Rosuvastatin) Rosuvastatin Impurity 7/Rosuvastatin tert-Butyl Ester/(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester Rosuvastatin calcium-11 R1.5 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)- ert-Butylrosuvastatin tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2- [methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5- dihydroxyhept-6-enoate(R2) tert-Butyl rosuvastatin,(3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,Methyl ester (+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulphonylamino)-Pyrimidin-5-Yl]-3,5-Dihydroxy-6(E)-Heptenate (R1.5 Or T-Butyl-Rosuvastatin) (+)-(3r,5s), Tert-Butyl 7-[4-(4-Fluorophenyl)-6-Isopropyl-2-... (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester tert-Butyl (6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate Rosuvastatin tert-butyl ester Rosuvastatin t-Butyl Ester (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester Rivastatin tert-butyl ester Rosuvastatin calcium impurity 10 (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2 [(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5 dihydroxyhept -6-enoic acid tert-butyl ester or (Tert Butyl Rosuvastatin) tert-Butyl Rosuvastatir Rosuvastatin EP Impurity 10 355806-00-7 C26H36FN3O6S Rosuvastatin intermediates Rosuvastatin Calcium and its intermediates