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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Structure
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride structure
CAS No.
58934-46-6
Chemical Name:
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride
Synonyms
Nsc310411;Lorcainide HCl;EINECS 261-504-6;Isocainide hydrochloride;LORCAINIDE HYDROCHLORIDE;4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride;N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP;Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride
CBNumber:
CB3904853
Molecular Formula:
C22H28Cl2N2O
Molecular Weight:
407.37652
MDL Number:
MOL File:
58934-46-6.mol
Last updated:2023-04-23 13:52:06
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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Properties

Melting point 263°
storage temp. -20°C
solubility Soluble in DMSO (up to 20 mg/ml), in Water (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form White solid.
color Powder
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 1 month
FDA UNII 1T1S98ONM1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar J67098 Lorcainide hydrochloride, 98% 58934-46-6 10mg $126 2021-12-16 Buy
American Custom Chemicals Corporation HCH0041839 N-(4-CHLOROPHENYL)-2-PHENYL-N-(1-PROPAN-2-YL-3,4,5,6-TETRAHYDRO-2H-PYRIDIN-4-YL)ACETAMIDE CHLORIDE 95.00% 58934-46-6 5MG $500.72 2021-12-16 Buy
Product number Packaging Price Buy
J67098 10mg $126 Buy
HCH0041839 5MG $500.72 Buy

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Chemical Properties,Uses,Production

Description

Lorcainide hydrochloride (58934-46-6) is a voltage-gated Na+?channel blocker.1?Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2?Acts at the ouabain binding site of guinea pig cardiac Na+/K+?ATPase and inhibits the enzyme (IC50?= 34 μM).3

Uses

Cardiac depressant (anti-arrhythmic).

References

1) Sheldon?et al.?(1989),?Antiarrhythmic drugs and the cardiac sodium channel: current models; Clin. Chem.,?35?748 2) Lynch?et al.?(1995),?Sodium channel clockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists; J. Pharmacol. Exp. Ther.,?273?554 3) Almotrefi?et al. (1999),?Class I antiarrhythmic drug effects on ouabain binding to guinea pig cardiac Na+ -K+ ATPase; Can. J. Physiol. Pharmacol.,?77?866

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Aladdin Scientific 		58
Shanghai EFE Biological Technology Co., Ltd. 58

58934-46-6(N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride)Related Search:

N-ETHYL-N-ISOPROPYLANILINE N,N-Dimethylpiperidin-4-amine 1,3-Propanediamine,N3,N3-diethyl-1-phenyl- 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 4-(dimethylammonio)piperidinium dichloride
4-Aminopiperidine dihydrochloride N,N,N',N'-TETRAMETHYL-1,3-BUTANEDIAMINE 2,N-DIPHENYLACETAMIDE 4-ACETAMIDOPIPERIDINE 1-Methyl-4-(methylamino)piperidine
N-(1-METHYLPIPERIDIN-4-YL)ANILINE 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl- N-Phenyl-N-(4-piperidinyl)propanamide admixture with HCl salt 1-ISOPROPYL-PIPERIDIN-4-YLAMINE Lorcainide
N-METHYL-N-4-PIPERIDINYLACETAMIDE 1-methyl-N-(2-phenylethyl)piperidin-4-amine N,N-DIMETHYL-2-PHENYLACETAMIDE

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N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride LORCAINIDE HYDROCHLORIDE Isocainide hydrochloride 4'-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide monohydrochloride Benzeneacetamide, N-(4-chlorophenyl)-N-[1-(1-methylethyl)-4-piperidinyl]-, monohydrochloride Nsc310411 N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride USP/EP/BP Lorcainide HCl EINECS 261-504-6 58934-46-6 C22H28Cl2N2O