ChemicalBook >> CAS DataBase List >>Bromo-PEG1-NH2 hydrobromide
Bromo-PEG1-NH2 hydrobromide
- CAS No.
- 2287287-20-9
- Chemical Name:
- Bromo-PEG1-NH2 hydrobromide
- Synonyms
- Bromo-PEG1-NH2 hydrobromide
- CBNumber:
- CB39405300
- Molecular Formula:
- C4H11Br2NO
- Molecular Weight:
- 248.95
- MDL Number:
- MOL File:
- 2287287-20-9.mol
Last updated:2023-05-04 15:13:58
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H335-H315-H318 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362 |
Bromo-PEG1-NH2 hydrobromide Chemical Properties,Uses,Production
Biological Activity
Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Bromo-PEG1-NH2 hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG1-NH2 hydrobromide Suppliers
Global( 1)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29778 | 58 |
| Supplier | Advantage |
|---|---|
| Beijing Jin Ming Biotechnology Co., Ltd. | 58 |
Bromo-PEG1-NH2 hydrobromide
2287287-20-9