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ChemicalBook >> CAS DataBase List >>Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester

Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester

Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester Structure
Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester structure
CAS No.
2222445-87-4
Chemical Name:
Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester
Synonyms
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D;Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester
CBNumber:
CB410659591
Molecular Formula:
C44H51ClN6O10
Molecular Weight:
859.36
MDL Number:
MOL File:
2222445-87-4.mol
Last updated:2024-11-19 20:33:22
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Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester Properties

Density 1.32±0.1 g/cm3(Predicted)
pka 10.83±0.46(Predicted)
form Solid
color White to light yellow

Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester Chemical Properties,Uses,Production

Biological Activity

MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19707 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705 qqyang@aikonchem.com China 10238 58
Supplier Advantage
Aladdin Scientific 		58
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 58

View Lastest Price from Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D pictures 2024-11-19 MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D
2222445-87-4
 US $0.00-0.00 / mg 10g TargetMol Chemicals Inc.
Carbamic acid, N-[2-[[[[(1S)-1-(chloromethyl)-2,3-dihydro-3-[[6-[[4-(methoxymethoxy)benzoyl]amino]imidazo[1,2-a]pyridin-2-yl]carbonyl]-9-methyl-1H-benz[e]indol-5-yl]oxy]carbonyl][2-(2-hydroxyethoxy)ethyl]amino]ethyl]-N-methyl-, 1,1-dimethylethyl ester MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D 2222445-87-4 C44H51ClN6O10