INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2490676-19-0
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- FTX-6058 hydrochloride
- CBNumber:
- CB411029250
- Molecular Formula:
- C22H19ClFN5O2
- Molecular Weight:
- 439.88
- MDL Number:
- MOL File:
- 2490676-19-0.mol
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Uses
Pociredir (FTX-6058) hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). Pociredir hydrochloride can induce HbF protein expression in cell and murine models. Pociredir hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].
Biological Activity
FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2]. FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].
References
[1]. Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 |
| Supplier | Advantage |
|---|---|
| Aladdin Scientific | 58 |