ChemicalBook >> CAS DataBase List >>NMK-TD 100

NMK-TD 100

CAS No.
1252802-38-2
Chemical Name:
NMK-TD 100
Synonyms
NMK-TD100;NMK-TD 100;NMK-TD-100;NMKTD100,NMK TD 100
CBNumber:
CB411075525
Molecular Formula:
C19H17N3O3S
Molecular Weight:
367.42
MDL Number:
MOL File:
1252802-38-2.mol
Last updated:2023-03-31 09:12:58

NMK-TD 100 Chemical Properties,Uses,Production

Description

NMK-TD-100 is a novel microtubule modulating agent. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 μM. The binding of NMK-TD-100 to tubulin was estimated to be ~10 times faster than that of colchicine. NMK-TD-100 exerted anti-proliferative activity by disrupting microtubule functions through tubulin binding and provided insights into its potential of being a chemotherapeutic agent.

NMK-TD 100 Preparation Products And Raw materials

Raw materials

Preparation Products

NMK-TD 100 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19696 58
NMK-TD100 NMK-TD-100 NMK-TD 100 NMKTD100,NMK TD 100 1252802-38-2