ChemicalBook >> CAS DataBase List >>N-[4-(-Carboxycyclohexylmethyl)]maleimide
N-[4-(-Carboxycyclohexylmethyl)]maleimide
- CAS No.
- 64987-82-2
- Chemical Name:
- N-[4-(-Carboxycyclohexylmethyl)]maleimide
- Synonyms
- Mal-Cyclohexanecarboxylicacid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl);4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid;4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%;4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid;4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid;4-(Maleimidomethyl)cyclohexanecarboxylic Acid (Discontinued, see C177860);4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid;Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-;4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid
- CBNumber:
- CB41176520
- Molecular Formula:
- C12H15NO4
- Molecular Weight:
- 237.25
- MDL Number:
- MFCD03093740
- MOL File:
- 64987-82-2.mol
- MSDS File:
- SDS
Last updated:2024-03-27 15:49:59
Melting point | 157-158°C |
---|---|
Boiling point | 433.6±18.0 °C(Predicted) |
Density | 1.329±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform, Methanol |
form | Solid |
pka | 4.80±0.10(Predicted) |
color | Pale Yellow |
InChI | InChI=1S/C12H15NO4/c14-10-5-6-11(15)13(10)7-8-1-3-9(4-2-8)12(16)17/h5-6,8-9H,1-4,7H2,(H,16,17) |
InChIKey | LQILVUYCDHSGEU-UHFFFAOYSA-N |
SMILES | C1(C(O)=O)CCC(CN2C(=O)C=CC2=O)CC1 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
HS Code | 2925.19.9100 | |||||||||
NFPA 704 |
|
N-[4-(-Carboxycyclohexylmethyl)]maleimide price More Price(19)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | M3218 | 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid | 64987-82-2 | 1G | $234 | 2024-03-01 | Buy |
TCI Chemical | M3218 | 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid | 64987-82-2 | 5G | $819 | 2024-03-01 | Buy |
TRC | C177860 | N-[4-(-Carboxycyclohexylmethyl)]maleimide | 64987-82-2 | 25mg | $110 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC19767 | N-[4-(-Carboxycyclohexylmethyl)]maleimide | 64987-82-2 | 5G | $150 | 2021-12-16 | Buy |
AK Scientific | J95578 | N-[4-(-Carboxycyclohexylmethyl)]maleimide | 64987-82-2 | 250mg | $160 | 2021-12-16 | Buy |
N-[4-(-Carboxycyclohexylmethyl)]maleimide Chemical Properties,Uses,Production
Description
4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Chemical Properties
White Solid
Uses
An amino reactive reagent.
Uses
A sulfhydryl crosslinking reagent.
Definition
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
N-[4-(-Carboxycyclohexylmethyl)]maleimide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 85)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hongxiong | +undefined18915499068 | Suzhouhongxiong@163.com | China | 120 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13182 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
Chemtour Biotech Co., Ltd | +8617327281506 | market@chemtour.com | China | 1460 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
View Lastest Price from N-[4-(-Carboxycyclohexylmethyl)]maleimide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-27 | Mal-Cyclohexanecarboxylicacid
64987-82-2
|
US $0.00 / g | 25g | >95.00% | 25g | Xian confluore Biological Technology Co., Ltd. |
- Mal-Cyclohexanecarboxylicacid
64987-82-2
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
64987-82-2(N-[4-(-Carboxycyclohexylmethyl)]maleimide)Related Search:
Maleimido-Tri(Ethylene Glycol)-Propionic Acid
Mal-PEG2-COOH
Mal-PEG4-Acid
Mal-PEG2-NHS ester
Bis-Mal-Lysine-PEG4-TFP ester
Maleimide-PEG4-NHS Ester
Maleimide-PEG2-NHS Ester
3-Maleimidopropionic acid
Mal-PEG2-acid
Mal-Amido-PEG4-acid
1of4
4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]Cyclohexanecarboxylic acid
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 95%
4-(N-MaleiMidoMethyl)cyclohexanecarboxylic acid
4-(Maleimidomethyl)cyclohexanecarboxylic Acid
(Discontinued, see C177860)
4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylic acid
4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid
4-((2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)
4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carboxylic acid
Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-
Mal-Cyclohexanecarboxylicacid
64987-82-2
Cross Linking Reagents
Maleimide Derivatives
MTS & Sulfhydryl Active Reagents
satralizumab-linker