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1,1,1-Trifluoroacetone

1,1,1-Trifluoroacetone Structure
1,1,1-Trifluoroacetone structure
CAS No.
421-50-1
Chemical Name:
1,1,1-Trifluoroacetone
Synonyms
TRIFLUOROACETONE;1,1,1-TRIFLUORO-2-PROPANONE;Methyl trifluoromethyl ketone;2-Propanone, 1,1,1-trifluoro-;CH3COCF3;1,1,1-TrifL;uoroacetone;Trilfuoroacetone;1,1,1-Trifluoroaceto;1,1,1-Trifluroacetone
CBNumber:
CB4123453
Molecular Formula:
C3H3F3O
Molecular Weight:
112.05
MDL Number:
MFCD00000423
MOL File:
421-50-1.mol
MSDS File:
SDS
Last updated:2025-03-10 17:18:44
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1,1,1-Trifluoroacetone Properties

Melting point -78 °C
Boiling point 22 °C(lit.)
Density 1.252 g/mL at 25 °C(lit.)
vapor pressure 13.62 psi ( 20 °C)
refractive index n20/D 1.3(lit.)
Flash point −23 °F
storage temp. 2-8°C
solubility Chloroform, Methanol
form Liquid
color Clear colorless
Water Solubility Miscible
Sensitive Lachrymatory
BRN 1748614
Stability Volatile
InChIKey FHUDAMLDXFJHJE-UHFFFAOYSA-N
CAS DataBase Reference 421-50-1(CAS DataBase Reference)
FDA UNII K987U5C2CX
NIST Chemistry Reference 2-Propanone, 1,1,1-trifluoro-(421-50-1)
EPA Substance Registry System 2-Propanone, 1,1,1-trifluoro- (421-50-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H224-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338-P403+P233
Hazard Codes  F+,Xi,F
Risk Statements  12-36/37/38
Safety Statements  16-26-29-33-36-7/9-9-37/39-39
RIDADR  UN 1993 3/PG 1
WGK Germany  3
F  19
Hazard Note  Flammable/Lachrymatory
TSCA  T
HazardClass  3
PackingGroup  I
HS Code  29147090
NFPA 704
4
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1,1,1-Trifluoroacetone price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T62804 1,1,1-Trifluoroacetone 97% 421-50-1 5g $45.6 2024-03-01 Buy
Sigma-Aldrich T62804 1,1,1-Trifluoroacetone 97% 421-50-1 25g $139 2024-03-01 Buy
TCI Chemical T2921 1,1,1-Trifluoroacetone (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)] 421-50-1 100G $385 2021-12-16 Buy
Alfa Aesar A13556 1,1,1-Trifluoroacetone, 95% 421-50-1 25g $122 2024-03-01 Buy
Alfa Aesar A13556 1,1,1-Trifluoroacetone, 95% 421-50-1 100g $351 2024-03-01 Buy
Product number Packaging Price Buy
T62804 5g $45.6 Buy
T62804 25g $139 Buy
T2921 100G $385 Buy
A13556 25g $122 Buy
A13556 100g $351 Buy

1,1,1-Trifluoroacetone Chemical Properties,Uses,Production

Chemical Properties

1,1,1-Trifluoroacetone is CLEAR COLOURLESS LIQUID

Uses

1,1,1-Trifluoroacetone is used as intermediate of bioactive substance and antihypertensive drug, and as effective synthetic building block and trifluoromethyl reaction reagent.

Uses

1,1,1-Trifluoroacetone is a general chemical reagent used in the synthesis of glucokinase-glucokinase regulatory protein) GK-GKRP disruptors which may act as potential targets for type II diabetics. Reactant for enantioselective cycloadditions.

Uses

Used in a synthesis of 2-trifluoromethyl-7-azaindoles starting with 2,6-dihalopyridines. The derived chiral imine was used to prepare enantiopure α-trifluoromethyl alanines and diamines via a Strecker reaction followed by either nitrile hydrolysis or reduction.

1,1,1-Trifluoroacetone Preparation Products And Raw materials

Raw materials

Preparation Products

4-Amino-2-(trifluoromethyl)quinoline 2-METHYL-4-TRIFLUOROMETHYL-NICOTINIC ACID 3-Thiophenecarboxylic acid, 2-amino-4-(trifluoromethyl)-, ethyl ester 2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBOXYLIC ACID trifluoromethylglyoxal-bis(guanylhydrazone)
2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBALDEHYDE Butanoic acid, 4,4,4-trifluoro-2,3-dihydroxy-3-methyl- HEXAFLUOROACETYLACETONE Ethyl 3-hydroxy-3-methyl-4,4,4-trifluorobutyrate 2-Butenoic acid, 4,4,4-trifluoro-3-methyl-, methyl ester
1,1,1-trifluoro-4-morpholin-4-yl-3-(morpholin-4-ylmethyl)butane-2,2-di ol 1,1,1,5,5,6,6,6-OCTAFLUORO-2,4-HEXANEDIONE

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1,1,1-Trifluoroacetone Suppliers

Global( 216)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13783527580 Lingzhiyue@aliyun.com China 3145 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531157085 abby@chuanghaibio.com China 8808 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12809 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5868 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-+86-371-66670886 info@dakenam.com China 19805 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21628 55
Fluoropharm Co., Ltd. 		+86-0571-85586753 +86-13336034509 sales@fluoropharm.com China 1445 60
Zjartschem 		+86-571 87238903 jocelynpan@zjarts.com CHINA 988 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29858 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Supplier Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Mujin Biotechnology Co.,Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Fluoropharm Co., Ltd. 		60
Zjartschem 		58
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from 1,1,1-Trifluoroacetone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1,1-Trifluoroacetone pictures 2025-04-27 1,1,1-Trifluoroacetone
421-50-1
 US $23.00 / kg 1kg 99% 200mt Jinan Finer Chemical Co., Ltd
1,1,1-Trifluoroacetone pictures 2025-04-23 1,1,1-Trifluoroacetone
421-50-1
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
1,1,1-Trifluoroacetone pictures 2025-03-21 1,1,1-Trifluoroacetone
421-50-1
 US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd

1,1,1-Trifluoroacetone Spectrum

1,1,1-Trifluoroacetone(421-50-1)MS1,1,1-Trifluoroacetone(421-50-1)1HNMR1,1,1-Trifluoroacetone(421-50-1)IR1

421-50-1(1,1,1-Trifluoroacetone)Related Search:

Citric acid monohydrate Acetylacetone Calcium pyruvate Thenoyltrifluoroacetone Pyruvic acid
Trifluoroacetic acid Triacetonamine 1,1,3-Trichloroacetone Trifluoroacetophenone Ethyl 4,4,4-trifluoroacetoacetate
ZIRCONIUM TRIFLUOROACETYLACETONATE 4,4,4-Trifluoro-1-phenyl-1,3-butanedione 3-BROMO-1,1,1-TRIFLUOROACETONE,1-BROMO-3,3,3-TRIFLUOROACETONE 97%,1-BROMO-3,3,3-TRIFLUOROACETONE,3-Bromo-1,1,1-trifluoroacetone, min. 97% Propiophenone Phenylacetone
METHYL TRIFLUOROPYRUVATE Ethyl trifluoropyruvate PALLADIUM(II) HEXAFLUOROACETYLACETONATE

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1,1,1-trifluoro-2-propanon 3,3,3-Trifluoroacetone CH3COCF3 Trifluoromethyl methyl ketone 1,1,1-TRIFLUOROACETONE TFK,1,1,1-Trifluoroaceto 1,1,1-Trifluoroacetone,95% 1,1,1-Trifluoroacetone, 98+% 1,1,1-Trifluroacetone 1,1,1,-Trifluoroacetone 98% 1,1,1-trifluoro-propan-2-one 1,1,1-TRIFLUOROACETONE, 60% IN WATER 1,1,1-Trifluoroacetone (TFK) 1,1,three 1-fluorideacetone 1,1,1-Trifluoroacetone (in cylinder without valve) [To use this product charged in cylinder, a valve is required which is sold separately (Product Code:V0030)] 1,1,1-Trifluoroacetone ,99% 1,1,1-Trifluoroaceto 1,1,1-TRIFLUOROACETONE FOR SYNTHESIS 1,1,1-TrifL uoroacetone Three fluorine acetone TRIFLUOROACETONE Methyl trifluoromethyl ketone 1,1,1-TRIFLUORO-2-PROPANONE 2-Propanone, 1,1,1-trifluoro- Trilfuoroacetone 1,1,1-Trifluoroacetone,97% 421-50-1 C3H3OF3 C3H3F3O CF3COCH3 KETONE Organic Building Blocks Ketones C3 to C6 Carbonyl Compounds Building Blocks C3 to C6 Carbonyl Compounds Ketones