Triethyl orthoformate
- CAS No.
- 122-51-0
- Chemical Name:
- Triethyl orthoformate
- Synonyms
- TRIETHOXYMETHANE;TEOF;ETHYL ORTHOFORMATE;orthoformate;ORTHOFORMIC ACID TRIETHYL ESTER;ETHONE;iethyl orthoforMate;1,1';TEOE;AETHON
- CBNumber:
- CB4126252
- Molecular Formula:
- C7H16O3
- Molecular Weight:
- 148.2
- MDL Number:
- MFCD00009230
- MOL File:
- 122-51-0.mol
- MSDS File:
- SDS
| Melting point | -76 °C (lit.) |
|---|---|
| Boiling point | 146 °C (lit.) |
| Density | 0.891 g/mL at 25 °C (lit.) |
| vapor density | 5.11 (vs air) |
| vapor pressure | 2.9 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | 86 °F |
| storage temp. | Flammables area |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless |
| Water Solubility | 1.35 g/L |
| Sensitive | Moisture Sensitive |
| Merck | 14,6884 |
| BRN | 605384 |
| Stability | Moisture Sensitive |
| InChIKey | GKASDNZWUGIAMG-UHFFFAOYSA-N |
| LogP | 1.2 at 20℃ |
| CAS DataBase Reference | 122-51-0(CAS DataBase Reference) |
| FDA UNII | 355LRR361Q |
| NIST Chemistry Reference | Ethyl orthoformate(122-51-0) |
| EPA Substance Registry System | Ethyl orthoformate (122-51-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 10-36-36/38 | |||||||||
| Safety Statements | 16-26-37/39-36-45-36/39 | |||||||||
| RIDADR | UN 2524 3/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | RM6475000 | |||||||||
| F | 21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159080 | |||||||||
| Toxicity | LD50 orally in rats: 7.06 g/kg (Smyth) | |||||||||
| NFPA 704 |
|
Triethyl orthoformate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T60453 | Triethyl orthoformate reagent grade, 98% | 122-51-0 | 18L | $1040 | 2024-03-01 | Buy |
| Sigma-Aldrich | 304050 | Triethyl orthoformate anhydrous, 98% | 122-51-0 | 2l | $262.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 304050 | Triethyl orthoformate anhydrous, 98% | 122-51-0 | 1l | $297 | 2024-03-01 | Buy |
| TCI Chemical | O0066 | Triethyl Orthoformate >98.0%(GC) | 122-51-0 | 25mL | $16 | 2024-03-01 | Buy |
| TCI Chemical | O0066 | Triethyl Orthoformate >98.0%(GC) | 122-51-0 | 500mL | $46 | 2024-03-01 | Buy |
Triethyl orthoformate Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid; pungent odor. Highly flammable. Slightly soluble in water; soluble in alcohol, ether; decomposes in water.
Uses
Triethyl orthoformate is used in Bodroux-Chichibabin aldehyde synthesis to prepare an aldehyde with one carbon higher by reacting with Grignard reagent. It is also used in the electrophilic formylation of activated aromatic species such as phenol.
Application
Sweet, somewhat camphoraceous-herbaceous odor with a Fimecdle-like note. Triethyl orthoformate has been suggested for use in industrial fragrances for masking, etc. and may find some application in that field. It tends to lift the odor of the conventional components of a pine fragrance and increase the radiation, an effect often desirable for masking purposes.
General Description
Triethyl orthoformate is a clear, colorless liquid with a pungent odor. Less dense than water. Flash point 86°F. Vapors heavier than air. May irritate skin and eyes. Used to make other chemicals.
Reactivity Profile
Triethyl orthoformate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Health Hazard
Triethyl orthoformate may cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Triethyl orthoformate will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
Safety Profile
Moderately toxic by ingestion. Mddly toxic by inhalation, skin contact, and subcutaneous routes. A skin and eye irritant. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidzing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.
Purification Methods
Fractionate triethyl orthoformate first at atmospheric pressure, then in a vacuum. If impure, then shake it with aqueous 2% NaOH, dry it with solid KOH and distil it from sodium through a 20cm Vigreux column (p 11). Alternatively, wash it with H2O, dry it over anhydrous K2CO3, filter and fractionate it through a Widmer column. [Sah & Ma J Am Chem Soc 54 2964 1932, Ohme & Schmitz Justus Liebigs Ann Chem 716 207 1968, Beilstein 2 IV 25.] IRRITANT and FLAMMABLE.
Triethyl orthoformate Preparation Products And Raw materials
Raw materials
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Preparation Products
1of8
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 | angelia@hbmojin.com | China | 1177 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Hangzhou Bayee Chemical Co., Ltd. | 0086-571-86990109 | rachelhoo@bayeechem.com | China | 104 | 55 |
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- Mar 31，2022
View Lastest Price from Triethyl orthoformate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-25 | Triethyl orthoformate
122-51-0
|
US $0.00 / KG | 1KG | 99.5% | 1000mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2024-11-22 | Triethyl Orthoformate
122-51-0
|
US $0.00 / Kg/Drum | 180KG | 99.4 | 1000kg | Ningxia Jinhua Chemical Co.,Ltd | |
 |
2024-10-31 | Triethyl Orthoformate
122-51-0
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- Triethyl orthoformate
122-51-0
- US $0.00 / KG
- 99.5%
- Jinan Finer Chemical Co., Ltd
-
- Triethyl Orthoformate
122-51-0
- US $0.00 / Kg/Drum
- 99.4
- Ningxia Jinhua Chemical Co.,Ltd
-
- Triethyl Orthoformate
122-51-0
- US $1.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd