S-(2-thiopyridyl)mercaptopropionohydrazide
- CAS No.
- 115616-51-8
- Chemical Name:
- S-(2-thiopyridyl)mercaptopropionohydrazide
- Synonyms
- 3-(2-Pyridyldisulfanyl)propanehydrazide;3-(pyridin-2-yldisulfanyl)propanehydrazide;S-(2-thiopyridyl)mercaptopropionohydrazide;3-(2-Pyridyldithio)propionylhydrazide(PDPH);Propanoic acid, 3-(2-pyridinyldithio)-, hydrazide
- CBNumber:
- CB41322297
- Molecular Formula:
- C8H11N3OS2
- Molecular Weight:
- 229.32
- MDL Number:
- MOL File:
- 115616-51-8.mol
Melting point | 87-90°C |
---|---|
Boiling point | 463.6±41.0 °C(Predicted) |
Density | 1.35±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 12.81±0.35(Predicted) |
color | White |
Stability | Light Sensitive |
FDA UNII | 4RHG5J9YPC |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319 |
Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
S-(2-thiopyridyl)mercaptopropionohydrazide price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 803480 | PDPH (3-(2-pyridyldithio)propionyl hydrazide) | 115616-51-8 | 50MG | $312 | 2023-06-20 | Buy |
TRC | P993040 | 3-(2-Pyridyldithio)propanoicAcidHydrazide | 115616-51-8 | 5mg | $140 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0009632 | 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE 95.00% | 115616-51-8 | 5MG | $774.4 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0009632 | 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE 95.00% | 115616-51-8 | 50MG | $1871.1 | 2021-12-16 | Buy |
S-(2-thiopyridyl)mercaptopropionohydrazide Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
A fluorescent sulfhydryl active reagent.
General Description
The PDPH is a heterobifunctional crosslinker containing sulfhydryl-reactive pyridyldithiol and carbonyl-reactive hydrazide moieties. Pyridyldithiols react with free sulfhydryls (-SH) to form disulfide bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, PDPH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Likewise, PDPH is useful as a sulfhydryl-addition reagent for glycoproteins and other carbohydrates; after reaction of the hydrazide to an oxidized carbohydrate, the pyridyldithiol group can be cleaved by a reducing agent to expose a sulfhydryl group. Yet another application for PDPH is to react the primary amine of the hydrazide moiety to a carboxyl group using the crosslinker EDC.
S-(2-thiopyridyl)mercaptopropionohydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
S-(2-thiopyridyl)mercaptopropionohydrazide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94658 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Aikon International Limited | 025-66113011 18112977050 | sales01@aikonchem.com | China | 16028 | 58 |
Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3250 | 58 |
Hefei Bomei Biotechnology Co., Ltd. | 13856598764 | 531626407@qq.com | China | 3008 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56086 | 58 |
Henan Alpha Chemical Co., Ltd. | 0371-0371-55055611 18137792234 | 3002694073@qq.com | China | 10399 | 58 |
Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1992 | 58 |