ES 8891
- CAS No.
- 129445-88-1
- Chemical Name:
- ES 8891
- Synonyms
- ES 8891;(3S,4S)-5-Cyclohexyl-3-hydroxy-4-[[(2S)-2-[[(2S)-2-(morpholinomethylcarbonylamino)-3-(1-naphthalenyl)propionyl]amino]-3-(4-thiazolyl)propionyl]amino]-N-hexylpentanamide
- CBNumber:
- CB41328370
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 129445-88-1.mol
ES 8891 Chemical Properties,Uses,Production
Description
ES 8891 is a renin inhibitor.
Uses
ES-8891 is a renin inhibitor. Oral administration of ES-8891 to normotensive sodium-depleted macaques for one week significantly reduced plasma renin activity, immunoreactive renin concentrations, and plasma angiotensin I concentrations, while mean blood pressure decreased significantly, without significant changes in heart rate. ES-8891 regulates blood pressure by inhibiting plasma renin levels and renal renin synthesis[1].
References
[1] YUTAKA KITAMI, KUNIO HIWADA, EIKI MURAKAMI, TAKERU IWATA, SHINJIRO MUNETA AND TATSUO KOKUBU"
ES 8891 Preparation Products And Raw materials
Raw materials
Preparation Products
ES 8891 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19725 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
