LG 83-6-05
- CAS No.
- 131602-24-9
- Chemical Name:
- LG 83-6-05
- Synonyms
- LG 83-6-05
- CBNumber:
- CB41341564
- Molecular Formula:
- C21H29NO3S
- Molecular Weight:
- 375.52486
- MDL Number:
- MOL File:
- 131602-24-9.mol
LG 83-6-05 Chemical Properties,Uses,Production
Description
LG 83-6-05 is a novel sodium channel blocking agent.
in vivo
In enzymatically-dispersed single ventricular cardiomyocytes of adult rats and guinea pigs the inhibition of the cardiac sodium current by a novel sodium channel blocking agent (LG 83-6-05, 1-[3-(2-Hydroxy-3-(2-methylpropylamino)-propoxy)-4-methyl-2- thienyl++ ]-3-phenyl-1-propanon hydrochloride) was studied. A single-electrode voltage-clamp system (switch clamping, patch electrodes) was used to measure action potentials as well as ionic currents during voltage-clamp experiments. In addition single channel measurements were performed using the patch-clamp technique. The single cell system enabled this study to demonstrate that LG 83-6-05 is an inhibitor of the cardiac sodium current._x000D_ _x000D_ Reference: Naunyn Schmiedebergs Arch Pharmacol. 1990 Nov;342(5):582-91. https://pubmed.ncbi.nlm.nih.gov/1965329/
target
LG 83-6-05 is a novel sodium channel blocking agent.
LG 83-6-05 Preparation Products And Raw materials
Raw materials
Preparation Products
LG 83-6-05 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19690 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23963 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Jinan ponder chemical co. LTD | 58 |
TargetMol Chemicals Inc. | 58 |